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TGM5

Official Full Name

transglutaminase 5
Overview

This gene encodes a member of the transglutaminase family. The encoded protein catalyzes formation of protein cross-links between glutamine and lysine residues, often resulting in stabilization of protein assemblies. This reaction is calcium dependent. Mutations in this gene have been associated with acral peeling skin syndrome.
Synonyms

TGM5; transglutaminase 5; protein-glutamine gamma-glutamyltransferase 5; TGX; Protein glutamine gamma glutamyltransferase 5; TGase 5; TGase X; TGase5; TGMX; Transglutaminase X; TG(X); TGase-5; transglutaminase V; transglutaminase-5; TGM6; TGASEX;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse

Source

E.coli
HEK293
HEK293T
Mammalian Cell
Mammalian cells

Tag

Flag
GST
His
His (Fc)
Avi
Myc
DDK
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	TGM5-3211H	Recombinant Human TGM5, GST-tagged	E.coli	GST	C-320aa	$319 / 25ug
Human	TGM5-1109HCL	Recombinant Human TGM5 293 Cell Lysate	HEK293	N/A		Inquiry
Human	TGM5-1771H	Recombinant Human TGM5 Protein, Myc/DDK-tagged, C13 and N15-labeled	HEK293T	Myc/DDK		Inquiry
Human	TGM5-2187H-B	Recombinant Human TGM5 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Human	TGM5-1869HFL	Recombinant Full Length Human TGM5 Protein, C-Flag-tagged	Mammalian cells	Flag		Inquiry
Human	TGM5-2187H	Recombinant Human TGM5 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	TGM5-16718M	Recombinant Mouse TGM5 Protein	Mammalian Cell	His		Inquiry
Mouse	Tgm5-6400M	Recombinant Mouse Tgm5 Protein, Myc/DDK-tagged	HEK293T	Myc/DDK		Inquiry
Mouse	TGM5-9170M	Recombinant Mouse TGM5 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	TGM5-9170M-B	Recombinant Mouse TGM5 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry

Involved Pathway
Protein Function
Interacting Protein
TGM5 Related Articles

TGM5 involved in several pathways and played different roles in them. We selected most pathways TGM5 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with TGM5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

TGM5 has several biochemical functions, for example, metal ion binding, protein-glutamine gamma-glutamyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TGM5 itself. We selected most functions TGM5 had, and list some proteins which have the same functions with TGM5. You can find most of the proteins on our site.

Function	Related Protein
metal ion binding	PFKM;LEPREL1;RNF187;ABO;ZNF71;PCGF5A;DDX11;ADCY7;RORCA
protein-glutamine gamma-glutamyltransferase activity	TGM5;TGM2A;TGM1L4;TGM2B;EPB4.2;F13A1A.1;F13A1B;TGM2;EPB42

TGM5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TGM5 here. Most of them are supplied by our site. Hope this information will be useful for your research of TGM5.

Senapati, S; Gutierrez-Achury, J; et al. Evaluation of European coeliac disease risk variants in a north Indian population. EUROPEAN JOURNAL OF HUMAN GENETICS 23:530-535(2015).

Salmi, TT; Hervonen, K; et al. Celiac disease evolving into dermatitis herpetiformis in patients adhering to normal or gluten-free diet. SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY 50:387-392(2015).