TGOLN2
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Official Full Name
trans-golgi network protein 2
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Overview
May be involved in regulating membrane traffic to and from trans-Golgi network. -
Synonyms
TGOLN2; trans-golgi network protein 2; TGN41; TGN46; Ttgn2; TGN38B; trans-Golgi network integral membrane protein 2;
- Cell & Tissue Lysates
- Recombinant Proteins
- Protein Pre-coupled Magnetic Beads
- Homo sapiens (Human)
- Human
- Mouse
- Rat
- E.coli
- E.coli expression system
- HEK293
- HEK293T
- Mammalian Cell
- Mammalian cells
- C
- His
- His (Fc)
- Avi
- Myc
- DDK
- N/A
- N
- Involved Pathway
- Protein Function
- Interacting Protein
TGOLN2 involved in several pathways and played different roles in them. We selected most pathways TGOLN2 participated on our site, such as Clathrin derived vesicle budding, Golgi Associated Vesicle Biogenesis, Membrane Trafficking, which may be useful for your reference. Also, other proteins which involved in the same pathway with TGOLN2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Clathrin derived vesicle budding | TPD52L1;BLOC1S6;APPB;PICALM;NAPAB;TGOLN2;FTH1A;CLINT1;CLTA |
| Golgi Associated Vesicle Biogenesis | BLOC1S6;TPD52;BLOC1S1;PICALM;TBC1D8B;PUM1;NECAP1;PPIAL4A;PICALMA |
| Membrane Trafficking | TRAPPC6B;MYO6;GJA5;EXOC6;SNX9;DTNBP1B;PLDN;NAPAB;MYO6B |
| Vesicle-mediated transport | SNX9;NAPG;AP1S3A;NAPB;COPE;GJB3;NECAP1;GJA5;PICALMB |
| trans-Golgi Network Vesicle Budding | PICALMA;BLOC1S6;GAK;TFR1B;YIPF6;SH3D19;DNASE2;AP3S1;CPD |
TGOLN2 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TGOLN2 itself. We selected most functions TGOLN2 had, and list some proteins which have the same functions with TGOLN2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | PPM1K;CNPY2;TTC9C;CEP70;KIF6;SERPINA1A;SNRNP70;UBR4;SMN1 |
TGOLN2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TGOLN2 here. Most of them are supplied by our site. Hope this information will be useful for your research of TGOLN2.
KRTAP10-9; ABL1; FYN; NCK1; PLCG1; PIK3R1; CRK; GRB2; AP2B1; PKMYT1; FURIN; IGF2R; MMP14; ATG9A; SYT2; NCSTN
- Q&As
- Reviews
Q&As (6)
Ask a questionTherapeutic strategies for TGOLN2 may include regulating its expression level, enhancing its transport capacity, and promoting or inhibiting its function. These methods may have potential application value in the treatment of mitochondria-related diseases and nervous system diseases.
In the nervous system, TGOLN2 may be involved in the energy metabolism and signal transduction process of neurons. It may maintain the normal function of neurons and signal transduction by transporting key tripeptide molecules.
The main function of TGOLN2 in cells is to transport tripeptides in mitochondria to maintain homeostasis levels of tripeptides in mitochondria. It maintains the normal function of mitochondria by recognizing and binding tripeptides on the inner membrane of mitochondria and transporting them to the mitochondrial matrix.
TGOLN2 can interact with a variety of other proteins, including mitochondrial tripeptide transporter 1, mitochondrial tripeptidase, etc. These interactions enable them to coordinate the transport and decomposition of tripeptides in mitochondria.
The structure of TGOLN2 determines its ability to recognize and bind tripeptides on the inner mitochondrial membrane, as well as where and how other proteins interact with it. The study of its structure can help us understand its function and mechanism of action.
The expression level of TGOLN2 can be increased through genetic engineering technology to promote the transport and decomposition of tripeptides in mitochondria, thereby improving the function of mitochondria. This may have potential application value in the treatment of mitochondria-related diseases and nervous system diseases.
Customer Reviews (3)
Write a reviewTGOLN2 exhibits good solubility in Western blot and can be easily dissolved in a variety of buffers.
It is easy to use, has high stability and has remarkable results.
High synthesis efficiency and yield.
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