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TH1L

Official Full Name

TH1-like
Overview

Negative Elongation Factor (NELF) consists of four subunits: WHSC2 (NELF-A), COBRA-1 (NELF-B), TH1L (NELF-C/D), and NELF-E. NELF, together with DRB-sensitivity inducing factor (DSIF), inhibits RNA Polymerase II (RNAPII) elongation resulting in RNAPII prom
Synonyms

TH1L; TH1-like (Drosophila); TH1 like (Drosophila homolog); negative elongation factor C/D; HSPC130; NELF C; NELF D; TH1; trihydrophobin 1; NELF-C/D; TH1-like protein; TH1 drosophila homolog; negative elongation factor proteins C and D; NELF-C; NELF-D;

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	TH1L-3212H	Recombinant Human TH1L, GST-tagged	E.coli	GST	C-term-350aa	$319 / 25ug
Human	TH1L-1769HCL	Recombinant Human TH1L cell lysate		N/A		Inquiry
Mouse	TH1L-16726M	Recombinant Mouse TH1L Protein	Mammalian Cell	His		Inquiry
Mouse	TH1L-9174M	Recombinant Mouse TH1L Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	TH1L-9174M-B	Recombinant Mouse TH1L Protein Pre-coupled Magnetic Beads	HEK293			Inquiry

Involved Pathway
Protein Function
Interacting Protein
TH1L Related Articles

TH1L involved in several pathways and played different roles in them. We selected most pathways TH1L participated on our site, such as Abortive elongation of HIV-1 transcript in the absence of Tat, Disease, Formation of HIV elongation complex in the absence of HIV Tat, which may be useful for your reference. Also, other proteins which involved in the same pathway with TH1L were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Abortive elongation of HIV-1 transcript in the absence of Tat	COBRA1;CTDP1;SUPT4H1;TH1L;SUPT5H;RDBP;WHSC2
Disease	MMADHC;CTDP1;EPM2A;KPNA3;CHMP4B;AP1M2;TNKS2;CFTR;PSTPIP2
Formation of HIV elongation complex in the absence of HIV Tat	ELL;TCEB3;RDBP;SUPT5H;CDK9;SUPT4H1;TCEA1;CTDP1;PSTPIP2
Formation of HIV-1 elongation complex containing HIV-1 Tat	CTDP1;TH1L;CDK9;ELL;SSRP1;RDBP;TCEA1;WHSC2;TCEB3
Formation of RNA Pol II elongation complex	ELL;SUPT5H;SSRP1;COBRA1;CTDP1;SUPT16H;CCNT2B;GM3258;CDK9
Formation of the Early Elongation Complex	TH1L;SUPT5H;COBRA1;RDBP;GM3258;NELFE;SUPT4H1;CTDP1;WHSC2
Formation of the HIV-1 Early Elongation Complex	RDBP;SUPT5H;SUPT4H1;CTDP1;TH1L;COBRA1;WHSC2
Gene Expression	ZNF791;SLC38A8;ZNF614;ZNF668;DNMT1;ZNF433;POLRMT;MED20;PDCD7

TH1L has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TH1L itself. We selected most functions TH1L had, and list some proteins which have the same functions with TH1L. You can find most of the proteins on our site.

Function	Related Protein
protein binding	C20orf20;PIK3R2;AGTRAP;ZFYVE21;RCBTB2;EPO;SHMT2;SPG20;TCL1A

TH1L has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TH1L here. Most of them are supplied by our site. Hope this information will be useful for your research of TH1L.

NELFA; ARAF; CACNA1A; PRMT5; EPRS; DNAJA1; ARPC4; SERF2; GSTM4; UBE3A; MTA1; SMAD4; AAMP; ZNF638

Loo, LWM; Tiirikainen, M; et al. Integrated analysis of genome-wide copy number alterations and gene expression in microsatellite stable, CpG island methylator phenotype-negative colon cancer. GENES CHROMOSOMES & CANCER 52:450-466(2013).

Antunes, AA; Leite, KR; et al. The Role of Prostate Specific Membrane Antigen and Pepsinogen C Tissue Expression as an Adjunctive Method to Prostate Cancer Diagnosis. JOURNAL OF UROLOGY 181:594-600(2009).