tmod2
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  • Official Full Name
  • tropomodulin 2 (neuronal)
  • Background
  • This gene encodes a neuronal-specific member of the tropomodulin family of actin-regulatory proteins. The encoded protein caps the pointed end of actin filaments preventing both elongation and depolymerization. The capping activity of this protein is dependent on its association with tropomyosin. Alternatively spliced transcript variants encoding different isoforms have been described.
  • Synonyms
  • TMOD2; tropomodulin 2 (neuronal); tropomodulin-2; NTMOD; Tropomodulin 2; MGC39481; N Tmod; Neuronal tropomodulin; tropomodulin 2 neuronal; N-TMOD
Cat.#:TMOD2-3304HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human TMOD2, His-tagged
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Cat.#:TMOD2-17105MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse TMOD2 Protein
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Cat.#:TMOD2-6183RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat TMOD2 Protein
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Cat.#:TMOD2-1035CTag:His
Source (Host):Mammalian CellsSpecies:Cynomolgus Monkey
Product nameRecombinant Cynomolgus TMOD2 Protein, His-tagged
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Cat.#:TMOD2-4851RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey TMOD2 Protein, His-tagged
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Cat.#:TMOD2-1327ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish TMOD2
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Cat.#:TMOD2-916HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human TMOD2 293 Cell Lysate
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Involved Pathway

TMOD2 involved in several pathways and played different roles in them. We selected most pathways TMOD2 participated on our site, such as Muscle contraction, Striated Muscle Contraction, which may be useful for your reference. Also, other proteins which involved in the same pathway with TMOD2 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Muscle contraction
MYBPC1; MYL6B; TMOD2; MYBPC2B; TNNI2A.4; TNNI2B.1; TMEM8C; LMOD1; MYL12B; TMOD4
Striated Muscle Contraction
TNNI1B; ACTA1B; DESMA; TNNI2B.1; MYLZ3; TNNI2A.3; TNNI2A.4; DMD; MYBPC3; VIML

Protein Function

TMOD2 has several biochemical functions, for example, actin binding, tropomyosin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TMOD2 itself. We selected most functions TMOD2 had, and list some proteins which have the same functions with TMOD2. You can find most of the proteins on our site.
Function
Related Protein
Function actin binding
Related Protein GCSAM; MACF1; CAPGA; CAPZA3; RUSC1; SYNE1; Fert2; LRRK2; LIMCH1; SPIRE1
Function tropomyosin binding
Related Protein CALD1; TMOD3; LMOD1; TNNT1; TNNT2A; S100A6; TMOD1; TMOD2; LMOD2A; NEBL

TMOD2 Related Articles

Moroz, N; Guillaud, L; et al. Mutations changing tropomodulin affinity for tropomyosin alter neurite formation and extension. PEERJ 1:-(2013).
Cox-Paulson, EA; Walck-Shannon, E; et al. Tropomodulin Protects alpha-Catenin-Dependent Junctional-Actin Networks under Stress during Epithelial Morphogenesis. CURRENT BIOLOGY 22:1500-1505(2012).