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TNPO3

Official Full Name

transportin 3
Overview

The protein encoded by this gene is a nuclear import receptor for serine/arginine-rich (SR) proteins such as the splicing factors SFRS1 and SFRS2. The encoded protein has also been shown to be involved in HIV-1 infection, apparently through interaction with the HIV-1 capsid protein. Two transcript variants encoding different isoforms as well as a noncoding transcript have been found for this gene.[provided by RefSeq, Jul 2010]
Synonyms

TNPO3; transportin 3; IPO12; TRNSR; LGMD1F; MTR10A; TRN-SR; TRN-SR2; transportin-3; imp12; importin 12; transportin-SR; limb girdle muscular dystrophy 1F (autosomal dominant);

Type

Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse
Rhesus Macaque
Zebrafish

Source

E.coli
HEK293
Mammalian Cell
Wheat Germ

Tag

GST
His
His (Fc)
Avi
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	TNPO3-31582TH	Recombinant Human TNPO3	Wheat Germ	N/A	255 amino acids	Inquiry
Human	TNPO3-3338H	Recombinant Human TNPO3, GST-tagged	E.coli	GST	C-term-350aa	$319 / 25ug
Mouse	TNPO3-17205M	Recombinant Mouse TNPO3 Protein	Mammalian Cell	His		Inquiry
Mouse	TNPO3-9504M-B	Recombinant Mouse TNPO3 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Mouse	TNPO3-9504M	Recombinant Mouse TNPO3 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rhesus Macaque	TNPO3-4884R	Recombinant Rhesus monkey TNPO3 Protein, His-tagged	Mammalian Cell	His		Inquiry
Rhesus Macaque	TNPO3-4698R	Recombinant Rhesus Macaque TNPO3 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rhesus Macaque	TNPO3-4698R-B	Recombinant Rhesus Macaque TNPO3 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Zebrafish	TNPO3-11310Z	Recombinant Zebrafish TNPO3	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein

TNPO3 involved in several pathways and played different roles in them. We selected most pathways TNPO3 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with TNPO3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

TNPO3 has several biochemical functions, for example, identical protein binding, nuclear localization sequence binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TNPO3 itself. We selected most functions TNPO3 had, and list some proteins which have the same functions with TNPO3. You can find most of the proteins on our site.

Function	Related Protein
identical protein binding	TARDBP;RASSF3;GLUD1;RASSF1;MPST;CREBZF;PAK2;HOOK1;SEPHS1
nuclear localization sequence binding	BRAP;KPNA5;IPO13;NUP214;KPNA1;NFKBIA;KPNB3;RANBP6;IPO4
protein binding	HOXB9;NUMB;SSRP1;FAM20C;LIMD1;KRT80;PDLIM2;GABPA;SMN1
protein transporter activity	AP4B1;ITGB1BP1;IPO7;RAMP1;PPIAL4A;KPNB3;IPO5;AP3S1;DSCR3
receptor activity	IL18R1;TLR4;OPN1SW;OR3A2;MED14;IL18RAP;F2RL1;CD1D;NOTCH1B

TNPO3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TNPO3 here. Most of them are supplied by our site. Hope this information will be useful for your research of TNPO3.

gag-pol; PTP4A3; USP19; MYC; C20orf24; BRF2; NEK6; PHLDA3; UBE2S; SMURF2; Ppp2r3a; Junb