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CRTC2

  • Official Full Name

    CREB regulated transcription coactivator 2

  • Overview

    Glucose homeostasis is regulated by hormones and cellular energy status. Elevations of blood glucose during feeding stimulate insulin release from pancreatic beta-cells through a glucose sensing pathway. Feeding also stimulates release of gut hormones suc
  • Synonyms

    CRTC2; CREB regulated transcription coactivator 2; CREB-regulated transcription coactivator 2; TORC2; transducer of regulated cAMP response element-binding protein (CREB) 2; TORC-2;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Rhesus Macaque
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • His|GST
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CRTC2-11594H Recombinant Human CRTC2, GST-tagged E.coli GST C-term-300a.a.
Human CRTC2-1918H Recombinant Human CRTC2 Protein, GST-tagged Wheat Germ GST
Human CRTC2-916H Recombinant Human CRTC2 Mammalian Cell His
Human CRTC2-7271HCL Recombinant Human CRTC2 293 Cell Lysate HEK293 N/A
Human CRTC2-11593H Recombinant Human CRTC2 protein, His-tagged E.coli His 394-693 aa
Human CRTC2-01C Recombinant Human CRTC2 Protein, GST tagged E.coli
Human CRTC2-2739H-B Recombinant Human CRTC2 Protein Pre-coupled Magnetic Beads HEK293
Human CRTC2-2123HF Recombinant Full Length Human CRTC2 Protein, GST-tagged In Vitro Cell Free System GST 693 amino acids
Human CRTC2-11595H Recombinant Human CRTC2 protein, His-GST-tagged E.coli His/GST Ala444-Gln693
Human CRTC2-2739H Recombinant Human CRTC2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human CRTC2-12H Recombinant Human CRTC2 Protein, GST tagged E.coli GST
Rhesus Macaque CRTC2-1035R Recombinant Rhesus monkey CRTC2 Protein, His-tagged Mammalian Cell His
Rhesus Macaque CRTC2-860R Recombinant Rhesus Macaque CRTC2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque CRTC2-860R-B Recombinant Rhesus Macaque CRTC2 Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • CRTC2 Related Research Area

CRTC2 involved in several pathways and played different roles in them. We selected most pathways CRTC2 participated on our site, such as PIK-Akt signaling pathway, AMPK signaling pathway, Insulin resistance, which may be useful for your reference. Also, other proteins which involved in the same pathway with CRTC2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
PIK-Akt signaling pathwayIFNA6;IL7R;HRAS;HSP90AB1;PCK1;IGF1R;CREB5;TSC2;COL6A6
AMPK signaling pathwayTSC2;CAB39L;PRKAB1;LEP;PPP2CB;CPT1C;SIRT1;PIK3R5;IGF1R
Insulin resistanceSOCS3B;PPP1CB;SLC2A4;PRKCZ;PPP1CBL;PPP1CC;PTPRF;PRKAG2A;FOXO1
HTLV-I infectionANAPC1;CRTC3;MAP3K1;CANX;TGFB3;PRKACB;SMAD3;IL15;HLA-DRB5

CRTC2 has several biochemical functions, for example, cAMP response element binding protein binding, chromatin binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CRTC2 itself. We selected most functions CRTC2 had, and list some proteins which have the same functions with CRTC2. You can find most of the proteins on our site.

Function Related Protein
cAMP response element binding protein bindingCRTC1A;KCNA3;CRTC1;DAPK3;DDIT3;CRTC2;CRTC3;CREM;ATF2
chromatin bindingEWSR1A;SP140;JMJD5;LOXL2;C19orf40;SUV39H1;PRMT6;CENPB;NKX6
protein bindingCRX;HELT;LSM4;DHX8;CACNG2;SIGLEC5;RNF4;CLPP;CYGB

CRTC2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CRTC2 here. Most of them are supplied by our site. Hope this information will be useful for your research of CRTC2.

YWHAB; bzlf1_ebvb9; SIK1; SIK3; YWHAG; CREBBP; Sec24c; MEIS1; CLTC; GTSE1

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