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TPI1

  • Official Full Name

    triosephosphate isomerase 1

  • Overview

    This gene encodes an enzyme, consisting of two identical proteins, which catalyzes the isomerization of glyceraldehydes 3-phosphate (G3P) and dihydroxy-acetone phosphate (DHAP) in glycolysis and gluconeogenesis. Mutations in this gene are associated with triosephosphate isomerase deficiency. Pseudogenes have been identified on chromosomes 1, 4, 6 and 7. Alternative splicing results in multiple transcript variants.
  • Synonyms

    TPI1; triosephosphate isomerase 1; triosephosphate isomerase; MGC88108; TIM; TPI 1; TPI; Triose phosphate isomerase 1; Triose phosphate isomerase; OTTHUMP00000165244; triose-phosphate isomerase;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • E.coli
  • HEK293
  • HEK293T
  • Mammalian Cell
  • Mammalian cells
  • Nicotiana Benthamiana
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • Strep
  • Myc
  • DDK
  • N/A
  • N
  • No tag
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human TPI1-31613TH Recombinant Human TPI1 N/A
Human TPI1-2845H Recombinant Human Triosephosphate Isomerase 1, His-tagged E.coli His
Human TPI1-305H Recombinant Human TPI1 Protein, His-tagged E.coli His
Human TPI1-846HCL Recombinant Human TPI1 293 Cell Lysate HEK293 N/A
Human TPI1-0193H Recombinant Human TPI1 Protein (M1-Q249), His/Strep tagged E.coli His/Strep M1-Q249
Human TPI1-10H Active Recombinant Human TPI1 Protein, His-tagged Nicotiana Benthamiana His
Human TPI1-640H Recombinant Human TPI1 Protein, His-tagged E.coli His Met1~Gln286
Human TPI1-2240H Recombinant Human TPI1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human TPI1-3012H Recombinant Human TPI1 protein, GST-tagged E.coli GST Met1-Gln249
Human TPI1-1300H Recombinant Human TPI1 Protein (M1-Q249), Tag Free E.coli No tag M1-Q249
Human TPI1-1400HFL Recombinant Full Length Human TPI1 Protein, C-Flag-tagged Mammalian cells Flag
Human TPI1-2240H-B Recombinant Human TPI1 Protein Pre-coupled Magnetic Beads HEK293
Human TPI1-6500H Recombinant Human TPI1 Protein (Met1-Gln249), N-His tagged E.coli N-His Met1-Gln249
Mouse TPI1-17254M Recombinant Mouse TPI1 Protein Mammalian Cell His
Mouse TPI1-9534M-B Recombinant Mouse TPI1 Protein Pre-coupled Magnetic Beads HEK293
Mouse TPI1-9534M Recombinant Mouse TPI1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Tpi1-6596M Recombinant Mouse Tpi1 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rat TPI1-6241R Recombinant Rat TPI1 Protein Mammalian Cell His
Rat TPI1-5898R-B Recombinant Rat TPI1 Protein Pre-coupled Magnetic Beads HEK293
Rat TPI1-5898R Recombinant Rat TPI1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Chicken TPI1-7001C Recombinant Chicken TPI1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

TPI1 involved in several pathways and played different roles in them. We selected most pathways TPI1 participated on our site, such as Glycolysis / Gluconeogenesis, Fructose and mannose metabolism, Inositol phosphate metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with TPI1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Glycolysis / GluconeogenesisLDHBA;ALDH3A1;PGK2;GPIB;LDHAL6A;ACSS2L;ADH1C;AKR1A1A;PDHB
Fructose and mannose metabolismTPI1A;ALDOAB;ALDOCA;DHRS13L1;AKR1B1;AKR1B8;FBP1A;GMPPB;Akr1b3
Inositol phosphate metabolismPIK3CD;TPI1A;MTMR3;MTMR7A;PI4K2B;PIP5K1C;PIP5K1AB;PTENB;PI4KA
Metabolic pathwaysPIK3C3;CYP7A1;IMPAD1;Atp5k;CYP19A1B;UQCR10;ITPKB;EXT1;ENPP3
Carbon metabolismACADS;ackA;ACO1;PDHA1B;GM5506;FBP1A;ALDOAA;EHHADH;ALDOB
Biosynthesis of amino acidsACY1;TKTL1;PRPS2;RPE;CBSA;ASS1;PGAM2;IDH2;ACO2

TPI1 has several biochemical functions, for example, protein binding, triose-phosphate isomerase activity, ubiquitin protein ligase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TPI1 itself. We selected most functions TPI1 had, and list some proteins which have the same functions with TPI1. You can find most of the proteins on our site.

Function Related Protein
protein bindingNPM3;ECE2;UTP11L;VRK2;DTX3;IL23R;IL15RA;AP2A1;ZNF496
triose-phosphate isomerase activityTPI1;TPI1A;TPI1B
ubiquitin protein ligase bindingFZD5;UBE2B;ERLIN2;FOXO1;MAP1LC3C;ANKRD32;VCL;RB1;JAK1

TPI1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TPI1 here. Most of them are supplied by our site. Hope this information will be useful for your research of TPI1.

PCNA; TERF1; SP1; YWHAZ; EGFR; CCL11; SETDB1; MAPK6; DDX24; POT1; LIPT1; ere_dna; GABARAP; NS; ATF2; polg_hcvh

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