TRAP1
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Official Full Name
TNF receptor-associated protein 1
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Overview
HSP90 proteins are highly conserved molecular chaperones that have key roles in signal transduction, protein folding,;protein degradation, and morphologic evolution. HSP90 proteins normally associate with other cochaperones and play;important roles in folding newly synthesized proteins or stabilizing and refolding denatured proteins after stress.;TRAP1 is a mitochondrial HSP90 protein. Other HSP90 proteins are found in cytosol (see HSP90AA1; MIM 140571) and;endoplasmic reticulum (HSP90B1; MIM 191175) (Chen et al., 2005 (PubMed 16269234)). -
Synonyms
TRAP1; TNF receptor-associated protein 1; heat shock protein 75 kDa, mitochondrial; HSP75; HSP90L; mitochondrial; Heat shock protein 75; Heat shock protein 75 kDa; Heat shock protein 75 kDa mitochondrial; HSP 75; HSP 90L; TNF receptor associated protein 1; TNFR associated protein 1; TNFR-associated protein 1; TRAP 1; TRAP-1; TRAP1_HUMAN; Tumor necrosis factor receptor associated protein; Tumor necrosis factor type 1 receptor associated protein; Tumor necrosis factor type 1 receptor-associated protein; OTTHUMP00000159796;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Chicken
- Human
- Mouse
- Rat
- Zebrafish
- E.coli
- HEK293
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- Flag
- GST
- His
- His (Fc)
- Avi
- N/A
- N
- Involved Pathway
- Protein Function
- Interacting Protein
- TRAP1 Related Articles
TRAP1 involved in several pathways and played different roles in them. We selected most pathways TRAP1 participated on our site, such as TGF-beta Receptor Signaling Pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with TRAP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| TGF-beta Receptor Signaling Pathway | HOXD9A;TRAP1;VDRB;COPS5;FOXH1;MEF2AA;EID2;RUNX2A;CTCF |
TRAP1 has several biochemical functions, for example, ATP binding, poly(A) RNA binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TRAP1 itself. We selected most functions TRAP1 had, and list some proteins which have the same functions with TRAP1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ATP binding | KIFC2;EPHB2B;ATP2A1L;NEK9;DMPK;PSMC1B;KIF21A;KIF1B;MCM6 |
| poly(A) RNA binding | MRPL15;DDX28;MARK2;EIF3H;WDR6;CLTC;RPP25L;RRP9;XRN1 |
| protein binding | TFAP2B;TNF;STARD10;NOP2;LRRFIP1;PPEF1;TRIM69;ARL2BP;ELF4 |
| protein kinase binding | TBC1D14;FAM83A;CYLD;FAM83E;GATA6;MAPKAP1;PTPN2;DAXX;CCNYL1 |
| tumor necrosis factor receptor binding | CASP8;FASLG;CD70;FADD;TNFSF13B;TNFSF9;TNFSF10;TNFSF10L;TNFSF15 |
| unfolded protein binding | HSP90AB1;SERPINH1;HSPA9;DNAJA1;DNAJB13;HSP90AA1.2;CCT6B;APCS;LMAN1 |
TRAP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TRAP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of TRAP1.
shepherdin_peptide; HLA-B; YWHAZ; Bles03; TPM3; q8ckx2_yerpe; ESX1; ileS; 15-deoxy-delta(12,14; ere_dna; KIF2A; C1qbp; GABARAP; MYC; FN1; 1C; CDK4; H2AFX; VCAM1
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