trim13
Share
  • Official Full Name
  • tripartite motif containing 13
  • Background
  • This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This gene is located on chromosome 13 within the minimal deletion region for B-cell chronic lymphocytic leukemia. Multiple alternatively spliced transcript variants have been found for this gene.
  • Synonyms
  • TRIM13; tripartite motif containing 13; ret finger protein 2 , RFP2, tripartite motif containing 13; E3 ubiquitin-protein ligase TRIM13; DLEU5; Leu5; RNF77; ret finger protein 2; RING finger protein 77; CLL-associated RING finger; tripartite motif protei
Cat.#:TRIM13-6270RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat TRIM13 Protein
+Inquiry
Cat.#:TRIM13-2783ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish TRIM13
+Inquiry
Cat.#:TRIM13-795HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human TRIM13 293 Cell Lysate
+Inquiry

Protein Function

TRIM13 has several biochemical functions, for example, ligase activity, protein binding, signal transducer activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TRIM13 itself. We selected most functions TRIM13 had, and list some proteins which have the same functions with TRIM13. You can find most of the proteins on our site.
Function
Related Protein
Function ligase activity
Related Protein TRAF2; SIAH1A; UHRF2; NEURL3; RNF212; NSMCE1; MUL1A; UBE2NB; GLULB; ZNRF3
Function protein binding
Related Protein TFIP11; LATS1; SZT2; KIF14; PINK1; EIF4A3; NCKAP1; NR4A2; MAP1LC3C; TBK1
Function signal transducer activity
Related Protein TAS2R113; FAM126A; HMOX1; TAS2R201.1; OLFR149; CXCR3.1; BAI2; OLFR481; SLC35B2; STAT5A
Function ubiquitin-protein transferase activity
Related Protein UBE2G2; BIRC8; BARD1; TRAF6; CBLL1; BIRC5A; LNX1; FBXO21; CNOT4B; RNF41
Function zinc ion binding
Related Protein ZDHHC18; MMP13A; ZADH2; TRIM47; MYLIPB; RFFL; LHX2; ZDHHC18B; WBP7; ZKSCAN5

Interacting Protein

TRIM13 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TRIM13 here. Most of them are supplied by our site. Hope this information will be useful for your research of TRIM13.
FLJ13057

TRIM13 Related Articles

Gatt, ME; Takada, K; et al. TRIM13 (RFP2) downregulation decreases tumour cell growth in multiple myeloma through inhibition of NF Kappa B pathway and proteasome activity. BRITISH JOURNAL OF HAEMATOLOGY 162:210-220(2013).
Zoumpoulidou, G; Broceno, C; et al. Role of the Tripartite Motif Protein 27 in Cancer Development. JOURNAL OF THE NATIONAL CANCER INSTITUTE 104:941-952(2012).