trip12
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  • Official Full Name
  • thyroid hormone receptor interactor 12
  • Background
  • Probable E3 ubiquitin-protein ligase TRIP12 is an enzyme that in humans is encoded by the TRIP12 gene.
  • Synonyms
  • TRIP12; thyroid hormone receptor interactor 12; probable E3 ubiquitin-protein ligase TRIP12; KIAA0045; MGC138849; MGC138850; Thyroid receptor interacting protein 12; TRIP 12; TRIP-12; TR-interacting protein 12; thyroid receptor-interacting protein 12; ULF
Cat.#:TRIP12-2771HTag:His/Myc
Source (Host):BaculovirusSpecies:Human
Product nameRecombinant Human TRIP12 Protein (1881-1992 aa), His-Myc-tagged
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Cat.#:TRIP12-3421HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human TRIP12, GST-tagged
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Cat.#:TRIP12-17408MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse TRIP12 Protein
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Cat.#:TRIP12-6289RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat TRIP12 Protein
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Involved Pathway

TRIP12 involved in several pathways and played different roles in them. We selected most pathways TRIP12 participated on our site, such as Ubiquitin mediated proteolysis, which may be useful for your reference. Also, other proteins which involved in the same pathway with TRIP12 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Ubiquitin mediated proteolysis
COP1; DET1; FZR1; UBR5; ANAPC11; FZR1A; TRIM32; UBE2E1; CUL5; HERC4

Protein Function

TRIP12 has several biochemical functions, for example, ligase activity, protein binding, thyroid hormone receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TRIP12 itself. We selected most functions TRIP12 had, and list some proteins which have the same functions with TRIP12. You can find most of the proteins on our site.
Function
Related Protein
Function ligase activity
Related Protein UBR4; TRIM37; UBE3B; GLULA; RNF181; E4F1; ACSM2; MID1; BIRC2; C12orf51
Function protein binding
Related Protein RCOR1; TNPO1; MPZL3; FGR; DHX58; MED27; NOX1; GPN3; TBATA; EIF2S2
Function thyroid hormone receptor binding
Related Protein MED24; MED4; FUS; OASL; NUP62; TAF11; HMGN3; PRMT2; NCOA3; ZNHIT3
Function ubiquitin protein ligase activity
Related Protein FANCF; RNF13; CMTM2A; HERC5; RNF126; HECTD1; UBE2N; TRIM37; RABGEF1; MYLIP
Function ubiquitin-protein transferase activity
Related Protein TRIP12; RNF31; NSMCE1; TRIM36; RNF20; RNF139; FBXL14; UBR3; CNOT4; FBXL6

Interacting Protein

TRIP12 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TRIP12 here. Most of them are supplied by our site. Hope this information will be useful for your research of TRIP12.
ESR1; USP11; USP7; PIH1D1; CARNS1; SMAD9; CLSTN1; ATF7IP; CELSR3; CFTR; SNW1; IFI16; RNF168