TRPA1
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Official Full Name
transient receptor potential cation channel, subfamily A, member 1
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Overview
The structure of the protein encoded by this gene is highly related to both the protein ankyrin and transmembrane proteins.The specific function of this protein has not yet been determined; however, studies indicate the function may involve a role in signal transduction and growth control. -
Synonyms
TRPA1; transient receptor potential cation channel, subfamily A, member 1; ANKTM1, ankyrin like with transmembrane domains 1; transient receptor potential cation channel subfamily A member 1; transformation-sensitive protein p120; ankyrin-like with trans;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Rat
- E. coli
- E.coli
- HEK293
- Mammalian cell
- Mammalian Cell
- Wheat Germ (in vitro)
- Flag,Strep II,8His
- His
- His (Fc)
- Avi
- Flag
- SUMO
- N/A
- N
- GST
- Involved Pathway
- Protein Function
- Interacting Protein
- TRPA1 Related Articles
TRPA1 involved in several pathways and played different roles in them. We selected most pathways TRPA1 participated on our site, such as Inflammatory mediator regulation of TRP channels, which may be useful for your reference. Also, other proteins which involved in the same pathway with TRPA1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Inflammatory mediator regulation of TRP channels | Adcy4;CYP2J5;PRKACG;CYP2C37;MAP2K3;PLCB4;PIK3CG;PIK3R2;PRKACA |
TRPA1 has several biochemical functions, for example, channel activity, intracellular ligand-gated calcium channel activity, temperature-gated cation channel activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TRPA1 itself. We selected most functions TRPA1 had, and list some proteins which have the same functions with TRPA1. You can find most of the proteins on our site.
Function | Related Protein |
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channel activity | APNL;CHRNB1;GJA8;BCL2;MAL;PANX2;BAX;TRPA1;STEAP1 |
intracellular ligand-gated calcium channel activity | AKR1C1;ITPR1;TRPA1;ITPR3;RYR2 |
temperature-gated cation channel activity | TRPA1;KCNK4 |
TRPA1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TRPA1 here. Most of them are supplied by our site. Hope this information will be useful for your research of TRPA1.
- Q&As
- Reviews
Q&As (7)
Ask a questionVariations in TRPA1 function can lead to chronic pain disorders and increased sensitivity to stimuli.
TRPA1 affects respiratory health, influencing asthma pathology and cough reflexes.
TRPA1 plays a crucial role in pain perception, particularly in detecting noxious stimuli.
TRPA1 contributes to the sensation of cold and mechanical forces, acting as a sensory receptor.
Activation of TRPA1 can trigger inflammatory and allergic reactions, amplifying immune responses.
TRPA1 modulates signal transduction in sensory neurons, playing a role in sensory perception.
TRPA1 acts as a sensor for environmental irritants, detecting a wide range of chemical stimuli.
Customer Reviews (3)
Write a reviewAccurate protein structural analysis, a critical component of our investigations.
Swift and reliable protein sequencing, indispensable for our research success.
Reliable mass spectrometry analysis, pivotal for our proteomics studies.
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