trpc1
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  • Official Full Name
  • transient receptor potential cation channel, subfamily C, member 1
  • Background
  • Transient receptor potential channel 1 (TRPC1) is a protein that in humans is encoded by the TRPC1 gene.
  • Synonyms
  • trpc1; transient receptor potential cation channel, subfamily C, member 1; HTRP 1; HTRP1; MGC133334; MGC133335; Mtrp1; Short transient receptor potential channel 1; Transient receptor potential cation channel subfamily C member 1; Transient receptor potential channel 1; Transient receptor protein 1; TRP 1; TRP 1 protein; Trp related protein 1; TRP-1; TRP1; TRP1 protein; Trpc1 transient receptor potential cation channel subfamily C member 1; TRPC1_HUMAN; Trrp1; transient receptor potential protein; xtrpc1
Cat.#:TRPC1-6299RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat TRPC1 Protein
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Cat.#:TRPC1-4987RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey TRPC1 Protein, His-tagged
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Cat.#:TRPC1-1227CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken TRPC1
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Cat.#:TRPC1-7834ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish TRPC1
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Cat.#:TRPC1-746HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human TRPC1 293 Cell Lysate
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Cat.#:CSC-RI0193Tag:
Source (Host):Species:Human
Product nameHuman TRPC1 Stable Cell Line-HEK293
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Involved Pathway

TRPC1 involved in several pathways and played different roles in them. We selected most pathways TRPC1 participated on our site, such as Glutamatergic synapse, Serotonergic synapse, Pancreatic secretion, which may be useful for your reference. Also, other proteins which involved in the same pathway with TRPC1 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Glutamatergic synapse
PRKCA; GRM6; GNAI3; GRM3; GRIN2D; SHANK1; SLC17A7; GNG10; HOMER1; PPP3CB
Serotonergic synapse
PLCB4; GNG7; GNAS; BRAF; CYP2C70; HTR5A; PRKACB; CYP2J5; SLC6A4; GNG2
Pancreatic secretion
CPA2; CPA3; CELA3A; AMY2B; AMY2A; RAB11A; ATP1A1; CLCA2; PLCB4; PRSS1

Protein Function

TRPC1 has several biochemical functions, for example, calcium channel activity, cation channel activity, inositol 1,4,5 trisphosphate binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TRPC1 itself. We selected most functions TRPC1 had, and list some proteins which have the same functions with TRPC1. You can find most of the proteins on our site.
Function
Related Protein
Function calcium channel activity
Related Protein TRPC2B; PDE2A; TRPV3; TRPC4A; TRPC7B; TRPV5; CACNA2D3; TRPC5A; RYR2; CACNA1SA
Function cation channel activity
Related Protein GAR1; ASIC4B; GRIN3B; ASIC3; TRPM1; TRPC1; TRPV4; CALHM3; PKD2L1; FAM26D
Function inositol 1,4,5 trisphosphate binding
Related Protein TRPC4; TRPC6A; AKR1C1; TRPC2; TRPC3; ITPR3; RPH3A; TRPC6; TRPC2B; CYTH2
Function ion channel binding
Related Protein YES1; CTNNB1; HTT; KCNJ11; PKP2; PKD1; SRC; KCNH1; KCNC1; RIMS1
Function protein binding
Related Protein FAM118A; PRRG2; GMIP; TGFB3; KCNJ3; FAM162A; KRT38; SLC3A1; UBE2H; Tnfrsf22
Function store-operated calcium channel activity
Related Protein TRPC7; TRPC5A; TRPC1; ORAI3; TRPC5; ZP3; TRPC2B; ORAI2; TRPC2; ORAI1

Interacting Protein

TRPC1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TRPC1 here. Most of them are supplied by our site. Hope this information will be useful for your research of TRPC1.
PKD2; MX1; q81xd6_bacan; o68752_yerpe; cya; yegQ; purL; carB; q5nel7_fratt; q5ni33_fratt; metE; q7cgs8_yerpe; pepP; ygfz_yerpe; proS; q7ch26_yerpe; q7chb5_yerpe; icmF1

TRPC1 Related Articles

Tran, VT; Ho, PT; et al. Mechanotransduction Channels of the Trabecular Meshwork. CURRENT EYE RESEARCH 39:291-303(2014).
Liu, YW; Schneider, MF; et al. FGF2 activates TRPC and Ca2+ signaling leading to satellite cell activation. FRONTIERS IN PHYSIOLOGY 5:-(2014).