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TSNAX

  • Official Full Name

    translin-associated factor X

  • Overview

    This gene encodes a protein which specifically interacts with translin, a DNA-binding protein that binds consensus sequences at breakpoint junctions of chromosomal translocations. The encoded protein contains bipartite nuclear targeting sequences that may provide nuclear transport for translin, which lacks any nuclear targeting motifs.
  • Synonyms

    TSNAX; translin-associated factor X; translin-associated protein X; TRAX; translin-like protein;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Cynomolgus Monkey
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • Mammalian Cell
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human TSNAX-380H Recombinant Human translin-associated factor X, His-tagged E.coli His
Human TSNAX-3451H Recombinant Human TSNAX, GST-tagged E.coli GST 1-290aa
Human TSNAX-715HCL Recombinant Human TSNAX 293 Cell Lysate HEK293 N/A
Human TSNAX-3572H Recombinant Human TSNAX Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Mouse TSNAX-17498M Recombinant Mouse TSNAX Protein Mammalian Cell His
Mouse TSNAX-9678M Recombinant Mouse TSNAX Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse TSNAX-9678M-B Recombinant Mouse TSNAX Protein Pre-coupled Magnetic Beads HEK293
Mouse Tsnax-6686M Recombinant Mouse Tsnax Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rat TSNAX-6321R Recombinant Rat TSNAX Protein Mammalian Cell His
Rat TSNAX-5977R Recombinant Rat TSNAX Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat TSNAX-5977R-B Recombinant Rat TSNAX Protein Pre-coupled Magnetic Beads HEK293
Cynomolgus Monkey TSNAX-1053C Recombinant Cynomolgus TSNAX Protein, His-tagged Mammalian Cell His
Cynomolgus Monkey TSNAX-796C Recombinant Cynomolgus Monkey TSNAX Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Cynomolgus Monkey TSNAX-796C-B Recombinant Cynomolgus Monkey TSNAX Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque TSNAX-4996R Recombinant Rhesus monkey TSNAX Protein, His-tagged Mammalian Cell His
Rhesus Macaque TSNAX-4810R Recombinant Rhesus Macaque TSNAX Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque TSNAX-4810R-B Recombinant Rhesus Macaque TSNAX Protein Pre-coupled Magnetic Beads HEK293
Zebrafish TSNAX-3234Z Recombinant Zebrafish TSNAX Mammalian Cell His
Chicken TSNAX-1545C Recombinant Chicken TSNAX Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • TSNAX Related Articles

TSNAX involved in several pathways and played different roles in them. We selected most pathways TSNAX participated on our site, such as Gene Expression, Gene Silencing by RNA, Small interfering RNA (siRNA) biogenesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with TSNAX were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Gene ExpressionNR5A1B;ZNF213;ZNF264;MED23;NRBF2;EEF1B2;CHD4;KRBOX4;AARS
Gene Silencing by RNADPY19L2;FKBP6;BARHL1;AGO3B;TSN;MYBL1;PIWIL4;ASZ1;TDRD1
Small interfering RNA (siRNA) biogenesisTSNAX;TARBP2;TSN

TSNAX has several biochemical functions, for example, DNA binding, endoribonuclease activity, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TSNAX itself. We selected most functions TSNAX had, and list some proteins which have the same functions with TSNAX. You can find most of the proteins on our site.

Function Related Protein
DNA bindingNKX2.9;UBN2B;BTBD11A;ANG3;ZFP2;NR2F5;TBX22;NTNG1;PLAGL1
endoribonuclease activityTSN;RNASEL;SMG6;RCL1;RNASET2;AGO2;TSNAX;CPSF3;NOB1
metal ion bindingVAV3;AMDHD1;HBAA1;RREB1;C1GALT1A;ZDHHC16A;XGB;KDM7AB;TGFBR2
poly(A) RNA bindingHMGB2;YTHDC2;SNIP1;FAM133B;RPS20;MYH9;LARP4B;FAM32A;RPF2
protein bindingATF7IP;RUVBL2;ZNF167;KHDRBS2;UBTD1;LRRC47;UBE2D2A;TSC2;PFKM
protein transporter activityDPY19L2;FRAG1;C11orf73;SEC61G;AP3S1;AP1G2;AP3S2;TSNAX;EIF4ENIF1
sequence-specific DNA bindingEVX1;NKX2.2A;NR5A5;HLF;HSFX1;FOXD4L1;FOXO4;MYBBP1A;NKX3.2
single-stranded DNA bindingLRPPRC;MEIOB;RPA4;SWSAP1;XRCC2;CDC45;HNRPDL;LONP1;RBMS1

TSNAX has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TSNAX here. Most of them are supplied by our site. Hope this information will be useful for your research of TSNAX.

AIMP1; KLC3; BLOC1S5; TCF12; LZTS2

Cheng, JY; Wang, SH; et al. Globo-H Ceramide Shed from Cancer Cells Triggers Translin-Associated Factor X-Dependent Angiogenesis. CANCER RESEARCH 74:6856-6866(2014).
Li, N; Zheng, J; et al. Identification of chimeric TSNAX-DISC1 resulting from intergenic splicing in endometrial carcinoma through high-throughput RNA sequencing. CARCINOGENESIS 35:2687-2697(2014).
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