TUBB4A
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Official Full Name
tubulin, beta 4A class IVa
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Synonyms
TUBB4A; tubulin, beta 4A class IVa; TUBB4, tubulin, beta 4 , tubulin, beta 4 class IVa; tubulin beta-4 chain; beta 5; class IVa beta tubulin; Beta 4; Beta 4 tubulin; MC1R; TBB4_HUMAN; TUB B4; TUBB 4; TUBB4; TUBB5; Tubulin 5 beta; Tubulin beta 3; Tubulin beta 4; Tubulin beta 4 chain; Tubulin beta 5; Tubulin beta IV; tubulin, beta, 5; class IVa beta-tubulin; tubulin, beta 4 class IVa; beta-5;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Cynomolgus Monkey
- Human
- Mouse
- E.coli
- HEK293
- HEK293T
- Mammalian Cell
- Mammalian cells
- Yeast
- Flag
- His
- His (Fc)
- Avi
- Myc
- DDK
- N/A
- Involved Pathway
- Protein Function
- Interacting Protein
TUBB4A involved in several pathways and played different roles in them. We selected most pathways TUBB4A participated on our site, such as Anchoring of the basal body to the plasma membrane, Assembly of the primary cilium, Cell Cycle, which may be useful for your reference. Also, other proteins which involved in the same pathway with TUBB4A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Anchoring of the basal body to the plasma membrane | CLASP1A;B9D1;TSGA14;CCDC41;MAPRE1A;RPGRIP1L;CEP63;SCLT1;CEP290 |
Assembly of the primary cilium | EXOC3;CCT2;CDK5RAP2;TCTEX1D1;DYNC1I2;NDE1;EXOC5;IFT22;NEK2 |
Cell Cycle | YWHABL;LMNB1;CEP164;MAD2L2;KAT5;PCNA;KIF2A;MPEG1.1;PDS5B |
Cell Cycle, Mitotic | DULLARD;STAG1;GOLGA2;NEK9;DYRK1A;ESCO1;CDKN1B;PLK4;DNA2 |
Centrosome maturation | ODF2;NDE1;CEP72;CEP70;MAPRE1B;HAUS2;NEDD1;TUBG1;NUMA1 |
Chaperonin-mediated protein folding | FBXW9;NOP56;CCT4;PFDN4;CCT5;PFDN6;FBXW5;TUBA1B;FBXL5 |
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding | TCP1;CCT2;TUBB4A;CCT5;CCT6A;CCT7;TUBA1B;PFDN5;TUBA3D |
Formation of tubulin folding intermediates by CCT/TriC | TUBA3D;TUBB4B;TUBA1B;CCT7;CCT8;CCT6A;CCT3;CCT2;TCP1 |
TUBB4A has several biochemical functions, for example, GTP binding, GTPase activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TUBB4A itself. We selected most functions TUBB4A had, and list some proteins which have the same functions with TUBB4A. You can find most of the proteins on our site.
Function | Related Protein |
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GTP binding | NME1;LRRK1;RASD1;RHOAA;RAB35;EHD4;RIT2;NMUR2;SAR1AB |
GTPase activity | SEPT5;RAB13;RRAD;RAB27B;RAB21;SEPT9;EEF1A1L2;ATL3;GNAI3 |
protein binding | PCDHA4;PRMT3;ITGAM;KANSL2;FADD;ATXN2;PCDH18;EHD3;RAB35 |
structural constituent of cytoskeleton | VILL;F-KER;KRT16;CYLC2;ARPC5;ARPC4;TUBA8L4;TLN1;ACTL7B |
TUBB4A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TUBB4A here. Most of them are supplied by our site. Hope this information will be useful for your research of TUBB4A.
LRRK2; P; NR4A1; a8k1f4_human; NFKB2; NFKBIE; IKBKB; CHUK; MAP3K7; RIPK2; TNFRSF1A; TNFRSF1B; NFKBIA; MAP3K8
- Q&As
- Reviews
Q&As (7)
Ask a questionTargeting TUBB4A could offer new treatments for neurodegenerative conditions by stabilizing neuronal structure.
TUBB4A, a tubulin isoform, is crucial for maintaining the cytoskeleton and cellular shape.
TUBB4A is important for brain function, involved in neuronal structure and signaling.
It plays a key role in assembling microtubules, essential for cell division and intracellular transport.
TUBB4A works with other cytoskeletal proteins to maintain cell structure and facilitate movement.
Mutations in TUBB4A can lead to a range of neurological conditions, affecting brain development and function.
Altered TUBB4A activity can disrupt microtubule dynamics, impacting cell function and stability.
Customer Reviews (3)
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