TXN2
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Official Full Name
thioredoxin 2
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Overview
This nuclear gene encodes a mitochondrial member of the thioredoxin family, a group of small multifunctional redox-active proteins. The encoded protein may play important roles in the regulation of the mitochondrial membrane potential and in protection against oxidant-induced apoptosis. -
Synonyms
TXN2; thioredoxin 2; thioredoxin, mitochondrial; MT TRX; thioredoxin-2; mitochondrial thioredoxin; MTRX; TRX2; MT-TRX;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Cattle
- Chicken
- Human
- Mouse
- Rat
- Zebrafish
- E.coli
- HEK293
- HEK293T
- Mammalian Cell
- GST
- His
- His (Fc)
- Avi
- His|T7
- Myc
- DDK
- Myc|DDK
- N/A
- Involved Pathway
- Protein Function
- Interacting Protein
- TXN2 Related Articles
TXN2 involved in several pathways and played different roles in them. We selected most pathways TXN2 participated on our site, such as Cellular responses to stress, Detoxification of Reactive Oxygen Species, Oxidative Stress, which may be useful for your reference. Also, other proteins which involved in the same pathway with TXN2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Cellular responses to stress | DNAJC7;LC3;HIST3H2BB;CDKN2A;PRDX3;CEBPB;DPF1;HSBP1;UVRAG |
| Detoxification of Reactive Oxygen Species | TXNRD2;TXN;Txn1;PRDX3;PRDX2;TXN2 |
| Oxidative Stress | NFIX;JUNBA;NOX4;TXNRD2;NQO1;TXN2 |
TXN2 has several biochemical functions, for example, oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor, peptide-methionine (R)-S-oxide reductase activity, peptide-methionine (S)-S-oxide reductase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TXN2 itself. We selected most functions TXN2 had, and list some proteins which have the same functions with TXN2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor | TXNDC8;ERO1L;ERO1LB;MSRB1B;TXN;TXN2;TXNL1;DNAJC10;MSRB1A |
| peptide-methionine (R)-S-oxide reductase activity | MSRB1;MSRB1A;MSRB2;MSRB1B;TXN2;MSRB3 |
| peptide-methionine (S)-S-oxide reductase activity | MSRB1A;MSRA;TXN2 |
| protein binding | VTI1B;ARL8A;ACTR6;EYA4;FST;SMAD2;UTP23;KIAA1530;GCC1 |
| protein complex binding | SKAP1;YWHAB;ADRB2;PPP2R2A;ERCC8;STRN;INS2;NCK2;PROS1 |
| protein disulfide oxidoreductase activity | PTGES2;TXN2;GLRX3;GRXCR1;CHCHD4;ERO1L;GLRX5;DNAJC10;TXNL1 |
TXN2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TXN2 here. Most of them are supplied by our site. Hope this information will be useful for your research of TXN2.
SSNA1; ZBTB14; TRIM21; DCTD; MAGEA11; RPIA; PSME3
- Q&As
- Reviews
Q&As (5)
Ask a questionYes, TXN2 is linked to the aging process and age-related diseases by its role in combating oxidative damage.
Autoimmune disorders like rheumatoid arthritis may involve TXN2 due to its influence on oxidative stress and inflammation.
It is a potential target, and research is exploring its therapeutic implications in diabetes management.
TXN2 levels can be altered in cancer cells, making it a candidate biomarker for cancer diagnosis and prognosis.
Yes, TXN2 has been implicated in cancer development as it can promote tumor growth by modulating redox signaling pathways.
Customer Reviews (3)
Write a reviewThey are readily available to address any concerns or questions and supply valuable resources to assist in experimental design and optimization.
Should I encounter any challenges or require technical assistance, the manufacturer provides prompt and knowledgeable support.
Their expertise in protein production and purification ensures the delivery of a high-quality product that consistently performs well in my experiments.
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