Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953 Learn More

TYW5

Official Full Name

tRNA-yW synthesizing protein 5
Synonyms

TYW5; tRNA-yW synthesizing protein 5; C2orf60, chromosome 2 open reading frame 60; tRNA wybutosine-synthesizing protein 5; FLJ37953; Chromosome 2 open reading frame 60; Hypothetical protein LOC129450; JmjC domain containing protein C2orf60; MGC70509; tRNA yW-synthesizing enzyme 5; jmjC domain-containing protein C2orf60; hTYW5; C2orf60;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse
Zebrafish

Source

E.coli
HEK293
HEK293T
Mammalian Cell

Tag

His
His (Fc)
Avi
Myc
DDK
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	TYW5-7069H	Recombinant Human TYW5, His-tagged	E.coli	His	1-315aa	Inquiry
Human	TYW5-8070HCL	Recombinant Human C2orf60 293 Cell Lysate	HEK293	N/A		Inquiry
Human	TYW5-6594H	Recombinant Human TYW5 Protein, Myc/DDK-tagged, C13 and N15-labeled	HEK293T	Myc/DDK		Inquiry
Mouse	TYW5-17680M	Recombinant Mouse TYW5 Protein	Mammalian Cell	His		Inquiry
Mouse	TYW5-9804M-B	Recombinant Mouse TYW5 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Mouse	TYW5-9804M	Recombinant Mouse TYW5 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	Tyw5-6762M	Recombinant Mouse Tyw5 Protein, Myc/DDK-tagged	HEK293T	Myc/DDK		Inquiry
Zebrafish	TYW5-4756Z	Recombinant Zebrafish TYW5	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein

TYW5 involved in several pathways and played different roles in them. We selected most pathways TYW5 participated on our site, such as Gene Expression, Synthesis of wybutosine at G37 of tRNA(Phe), tRNA modification in the nucleus and cytosol, which may be useful for your reference. Also, other proteins which involved in the same pathway with TYW5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Gene Expression	HNRNPH2;TAF1C;ZNF2;RXRBB;DNMT1;ZNF350;SF3A1;NR0B2A;COX18
Synthesis of wybutosine at G37 of tRNA(Phe)	TRMT5;TYW5;TRMT12;LCMT2;TYW1;TYW3
tRNA modification in the nucleus and cytosol	ADAT2;TP53RK;OSGEP;ADAT3;PUS7;TRMT112;THG1L;PUS1;LAGE3
tRNA processing	TRMT5;TRMT112;RPP38;CCDC76;WDR4;TRMT44;RPP30;NSUN2;TSEN54

TYW5 has several biochemical functions, for example, iron ion binding, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors, protein homodimerization activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TYW5 itself. We selected most functions TYW5 had, and list some proteins which have the same functions with TYW5. You can find most of the proteins on our site.

Function	Related Protein
iron ion binding	Agmo;CYP19A1A;CYP2AA3;CYP2U1;ISCU;CYP2K18;CYP2D10;CYP1B1;CYP2X8
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors	ALKBH8;PHF8;JHDM1D;KDM5D;ALKBH5;KDM5BA;C14orf169;EGLN2;ALKBH4
protein homodimerization activity	IKBKB;TARBP2;G6PDX;ALS2;PSPH;S100B;MTPAP;VEGFA;ZBTB16
tRNA binding	SSB;TRMT1L;YARS;DARS2;TYW5;RARS;IFIT5;TRMU;CTU2

TYW5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TYW5 here. Most of them are supplied by our site. Hope this information will be useful for your research of TYW5.