|Official Full Name||ubiquitin-conjugating enzyme E2, J1|
|Background||The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is located in the membrane of the endoplasmic reticulum (ER) and may contribute to quality control ER-associated degradation by the ubiquitin-proteasome system. [provided by RefSeq, Jul 2008]|
|Synonyms||UBE2J1; ubiquitin-conjugating enzyme E2, J1; UBC6; Ubc6p; CGI-76; NCUBE1; HSPC153; HSPC205; NCUBE-1; HSU93243; ubiquitin-conjugating enzyme E2 J1; HSUBC6e; ubiquitin-conjugating enzyme E2, J1, U; non-canonical ubiquitin-conjugating enzyme 1; yeast ubiquitin-conjugating enzyme UBC6 homolog E; ubiquitin-conjugating enzyme E2, J1 (UBC6 homolog, yeast);|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
UBE2J1 involved in several pathways and played different roles in them. We selected most pathways UBE2J1 participated on our site, such as Ubiquitin mediated proteolysis, Protein processing in endoplasmic reticulum, Parkinsons disease, which may be useful for your reference. Also, other proteins which involved in the same pathway with UBE2J1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Ubiquitin mediated proteolysis||UBA6; HERC2; PIAS4A; UBOX5; BRCA1; FZR1A; CDC16; BIRC2; CDC34A; CUL3|
|Protein processing in endoplasmic reticulum||HSP70; RNF5; DNAJC5G; DAD1; MAN1C1; ATF4; MBTPS1; UBE2E2; SEC23B; PRKCSH|
|Parkinsons disease||COX5A; NDUFA4; NDUFS8; COX7A1; UBE2G1; UBE2J1; PPIF; PRKACA; PRKACG; NDUFAB1|
UBE2J1 has several biochemical functions, for example, ATP binding, ubiquitin conjugating enzyme activity, ubiquitin protein ligase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by UBE2J1 itself. We selected most functions UBE2J1 had, and list some proteins which have the same functions with UBE2J1. You can find most of the proteins on our site.
|ATP binding||ATP8A1; NLRC3; WEE2; HIPK4; ORC4; PFKFB2A; HSPA7; CHD4A; UBE2Q2; ATP9B|
|ubiquitin conjugating enzyme activity||UBE2C; UBE2E2; UBE2Q1; UBE2S; UBE2D3; UBE2D2; UBE2J2; UBE2A; UBE2E3; UBE2R2|
|ubiquitin protein ligase activity||CMTM2A; STUB1; ZNRF1; TRIM6; MED27; RAD18; UBE2H; LRSAM1; UHRF2; RNF2|
|ubiquitin protein ligase binding||FOXO1; MYOD1; PRDX6; BAG4; TNFRSF1B; CUL3A; MID1; SNX9; HDAC6; PACRG|
UBE2J1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with UBE2J1 here. Most of them are supplied by our site. Hope this information will be useful for your research of UBE2J1.
Map3k1; PJA2; CREB3; TRIM27; UBA1; BRCA1; BIRC2; q6nr77_human; LRSAM1; SYVN1; RNF2; TOPORS; RNF5