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UBE2Q1

Official Full Name

ubiquitin-conjugating enzyme E2Q family member 1
Overview

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s), and ubiquitin-protein ligases (E3s). This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein is 98% identical to the mouse counterpart.
Synonyms

UBE2Q1; ubiquitin-conjugating enzyme E2Q family member 1; UBE2Q, ubiquitin conjugating enzyme E2Q (putative); ubiquitin-conjugating enzyme E2 Q1; NICE 5; PRO3094; Galactosyl transferase associated protein; GTAP; NICE5; OTTHUMP00000035378; Protein NICE 5; Protein NICE-5; UB2Q1_HUMAN; UBE2Q; Ubiquitin carrier protein Q1; Ubiquitin conjugating enzyme E2 Q1; Ubiquitin conjugating enzyme E2Q (putative) 1; Ubiquitin conjugating enzyme E2Q 1; Ubiquitin conjugating enzyme E2Q family member 1; Ubiquitin protein ligase Q1; Ubiquitin-protein ligase Q1; galactosyl transferase-associated protein; ubiquitin-conjugating enzyme E2Q (putative) 1; NICE-5;

Type

Recombinant Proteins
Cell & Tissue Lysates

Species

Human
Mouse
Zebrafish

Source

E.coli
HEK293
HEK293T
Mammalian Cell

Tag

His
Strep
Myc
DDK
N/A
No tag

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	UBE2Q1-3542H	Recombinant Human UBE2Q1, His-tagged	E.coli	His	C-term-165aa	$319 / 25ug
Human	UBE2Q1-565HCL	Recombinant Human UBE2Q1 293 Cell Lysate	HEK293	N/A		Inquiry
Human	UBE2Q1-0235H	Recombinant Human UBE2Q1 Protein (Q2-G422), His/Strep tagged	E.coli	His/Strep	Q2-G422	Inquiry
Human	UBE2Q1-0234H	Recombinant Human UBE2Q1 Protein (Q2-G422), Tag Free	E.coli	No tag	Q2-G422	Inquiry
Mouse	Ube2q1-6796M	Recombinant Mouse Ube2q1 Protein, Myc/DDK-tagged	HEK293T	Myc/DDK		Inquiry
Zebrafish	UBE2Q1-2761Z	Recombinant Zebrafish UBE2Q1	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein

UBE2Q1 involved in several pathways and played different roles in them. We selected most pathways UBE2Q1 participated on our site, such as Ubiquitin mediated proteolysis, which may be useful for your reference. Also, other proteins which involved in the same pathway with UBE2Q1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Ubiquitin mediated proteolysis	UBE2NB;SOCS1;CUL1;KEAP1B;UBE2D3;BIRC3;UBA2;UBE3B;UBE2R2

UBE2Q1 has several biochemical functions, for example, ATP binding, protein binding, ubiquitin conjugating enzyme activity. Some of the functions are cooperated with other proteins, some of the functions could acted by UBE2Q1 itself. We selected most functions UBE2Q1 had, and list some proteins which have the same functions with UBE2Q1. You can find most of the proteins on our site.

Function	Related Protein
ATP binding	RYK;MCM3L;NEK4;AURKC;GSS;ROS1;STK19;TUT1;NEK6
protein binding	C16orf5;CSTF2T;MAPK10;ZNHIT3;COMMD5;PNRC2;CDH5;C10orf119;SUPT6H
ubiquitin conjugating enzyme activity	UBE2Q2;UBE2Q1;UBE2D4;UBE2D2;UBE2J2;UBE2D1;UBE2C;UBE2Z;UBE2O

UBE2Q1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with UBE2Q1 here. Most of them are supplied by our site. Hope this information will be useful for your research of UBE2Q1.

STUB1; EXOSC7; RNF26; IRF2BPL; RNF7; USP11; SNW1