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UCK1

  • Official Full Name

    uridine-cytidine kinase 1

  • Overview

    This gene encodes a uridine-cytidine kinase that catalyzes the phosphorylation of uridine and cytidine to uridine;monophosphate (UMP) and cytidine monophosphate (CMP) but not the phosphorylation of deoxyribonucleosides or purine;ribonucleosides. This enzyme can also phosphorylate uridine and cytidine analogs and uses both ATP and GTP as a;phosphate donor. Alternative splicing results in multiple splice variants encoding distinct isoforms.
  • Synonyms

    UCK1; uridine-cytidine kinase 1; FLJ12255; URK1; Cytidine monophosphate kinase; Cytidine monophosphokinase 1; Cytidylate kinase; Deoxycytidylate kinase; OTTHUMP00000022400; OTTHUMP00000022401; OTTHUMP00000022403; OTTHUMP00000022404; RP11-334J6.5; UCK 1; UCK1_HUMAN; UMP-CMP kinase; Uridine monophosphokinase 1;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • Mammalian Cell
  • Mammalian cells
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • SUMO
  • Myc
  • DDK
  • Myc|DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human UCK1-199H Recombinant Human UCK1, His-tagged E.coli His 143-273aa
Human UCK1-3574H Recombinant Human UCK1, GST-tagged E.coli GST 1-201aa
Human UCK1-2337H Recombinant Human UCK1 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human UCK1-532HCL Recombinant Human UCK1 293 Cell Lysate HEK293 N/A
Human UCK1-892H Recombinant Human UCK1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human UCK1-1146HFL Recombinant Full Length Human UCK1 Protein, C-Flag-tagged Mammalian cells Flag
Human UCK1-2305H-B Recombinant Human UCK1 Protein Pre-coupled Magnetic Beads HEK293
Human UCK1-3646H Recombinant Human UCK1 protein, His-SUMO-tagged E.coli His-SUMO 1-201aa
Human UCK1-529H Recombinant Human UCK1 Protein, His-tagged E.coli N-His Ala91-His277
Human UCK1-2305H Recombinant Human UCK1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Uck1-6822M Recombinant Mouse Uck1 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse Uck1-530M Recombinant Mouse Uck1 Protein, His&GST-tagged E.coli N-His&GST Lys42-His277
Rhesus Macaque UCK1-5087R Recombinant Rhesus monkey UCK1 Protein, His-tagged Mammalian Cell His
Rhesus Macaque UCK1-4900R Recombinant Rhesus Macaque UCK1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque UCK1-4900R-B Recombinant Rhesus Macaque UCK1 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish UCK1-1376Z Recombinant Zebrafish UCK1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

UCK1 involved in several pathways and played different roles in them. We selected most pathways UCK1 participated on our site, such as Pyrimidine metabolism, Drug metabolism - other enzymes, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with UCK1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Pyrimidine metabolismTYMP;TRR1;RRM1;TXNRD2;NME5;NME6;POLR3K;PRIM1;CTPS2
Drug metabolism - other enzymesIMPDH1B;UCK2A;DPYDB;UGT1A7C;CES2;CDA;UGT2B7;IMPDH1A;UGT1A2
Metabolic pathwaysPRPS1L1;GOT2A;B4GALT3;INPP5L;GALE;NDUFA1;LIPT2;PRPS1;DPM1

UCK1 has several biochemical functions, for example, ATP binding, nucleoside kinase activity, uridine kinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by UCK1 itself. We selected most functions UCK1 had, and list some proteins which have the same functions with UCK1. You can find most of the proteins on our site.

Function Related Protein
ATP bindingKIF7;UBE2C;CDK5;HSPA1A;DDX28;HIPK1;PDPK1A;TNK2;ATP8B3
nucleoside kinase activityUCK2A;TK1;UCK2;DCK;DGUOK;UCK2B;UCK1
uridine kinase activityUCK2B;CMPK1;UPRT;UCKL1;UCK2A;UCK2;UCK1;UCKL1A

UCK1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with UCK1 here. Most of them are supplied by our site. Hope this information will be useful for your research of UCK1.

ezrA; PLA2G12A

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