uimc1
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  • Official Full Name
  • ubiquitin interaction motif containing 1
  • Background
  • BRCA1-A complex subunit RAP80 is a protein that in humans is encoded by the UIMC1 gene.
  • Synonyms
  • UIMC1; ubiquitin interaction motif containing 1; BRCA1-A complex subunit RAP80; RAP80; receptor associated protein 80; receptor-associated protein 80; retinoid x receptor interacting protein; retinoid X receptor-interacting protein 110; ubiquitin interact
Cat.#:UIMC1-17830MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse UIMC1 Protein
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Cat.#:UIMC1-6440RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat UIMC1 Protein
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Cat.#:UIMC1-506HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human UIMC1 293 Cell Lysate
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Involved Pathway

UIMC1 involved in several pathways and played different roles in them. We selected most pathways UIMC1 participated on our site, such as Cell Cycle, Cell Cycle Checkpoints, DNA Double Strand Break Response, which may be useful for your reference. Also, other proteins which involved in the same pathway with UIMC1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Cell Cycle
DMC1; NUDC; ITGB3BP; CDC26; SKA2; DSN1; DCTN1A; PDS5A; ARPP19; GORASP1
Cell Cycle Checkpoints
HUS1; BRE; CDKN1B; RAD17; BABAM1; BRCC3; RAD9A; RAD9; THRSP; UIMC1
DNA Double Strand Break Response
THRSP; BAZ1B; TP53BP1; KDM4B; UBE2V2; RNF168; EYA2; BARD1; HTATIP; CHEK2
DNA Double-Strand Break Repair
RAD9A; FAM175A; PARP2; RNF4; KDM4A; CHEK2; POLD3; PAXIP1; BAZ1B; EYA2
DNA Repair
CHEK1; PPIE; EYA2; POLD3; RNF168; KIAA0101; RAD1; BARD1; HUS1; UBE2L6
G2/M Checkpoints
BARD1; RAD9; BRE; BABAM1; RAD9B; FAM175A; RAD1; TP53BP1; BRCC3; RAD17
G2/M DNA damage checkpoint
FAM175A; BRE; RNF168; BABAM1; BRCC3; UIMC1; TP53BP1; BARD1; THRSP
HDR through Homologous Recombination (HR) or Single Strand Annealing (SSA)
RAD51AP1; PPP4R2; UIMC1; TOPBP1; BRE; PPP4R2A; PPP4CB; GEN1; RAD1; RNF168

Protein Function

UIMC1 has several biochemical functions, for example, K63-linked polyubiquitin binding, histone binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by UIMC1 itself. We selected most functions UIMC1 had, and list some proteins which have the same functions with UIMC1. You can find most of the proteins on our site.
Function
Related Protein
Function K63-linked polyubiquitin binding
Related Protein ZRANB1; ZRANB1B; TAB2; TNFAIP3; ZRANB3; RNF168; SPRTN; IKBKG; RNF169; SQSTM1
Function histone binding
Related Protein HIST1H3G; ASF1B; CD1d1; HIST1H3E; H3F3A; L3MBTL2; PRMT6; CHAF1B; NASP; BRDT
Function protein binding
Related Protein ACAD9; PTPRJ; USP28; DNAJB6; PICK1; KTN1; GRIN2C; NRIP2; DYNC1I1; HERC5

Interacting Protein

UIMC1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with UIMC1 here. Most of them are supplied by our site. Hope this information will be useful for your research of UIMC1.
FAM175A; BRCA1; PYCRL; CASK