UIMC1
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Official Full Name
ubiquitin interaction motif containing 1
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Overview
BRCA1-A complex subunit RAP80 is a protein that in humans is encoded by the UIMC1 gene. -
Synonyms
UIMC1; ubiquitin interaction motif containing 1; BRCA1-A complex subunit RAP80; RAP80; receptor associated protein 80; receptor-associated protein 80; retinoid x receptor interacting protein; retinoid X receptor-interacting protein 110; ubiquitin interact;
- Cell & Tissue Lysates
- Recombinant Proteins
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Rat
- HEK293
- Mammalian Cell
- His
- His (Fc)
- Avi
- N/A
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | UIMC1-506HCL | Recombinant Human UIMC1 293 Cell Lysate | HEK293 | N/A |
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| Mouse | UIMC1-17830M | Recombinant Mouse UIMC1 Protein | Mammalian Cell | His |
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| Mouse | UIMC1-9901M | Recombinant Mouse UIMC1 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
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| Mouse | UIMC1-9901M-B | Recombinant Mouse UIMC1 Protein Pre-coupled Magnetic Beads | HEK293 |
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| Rat | UIMC1-6440R | Recombinant Rat UIMC1 Protein | Mammalian Cell | His |
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| Rat | UIMC1-6096R-B | Recombinant Rat UIMC1 Protein Pre-coupled Magnetic Beads | HEK293 |
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| Rat | UIMC1-6096R | Recombinant Rat UIMC1 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
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- Involved Pathway
- Protein Function
- Interacting Protein
- UIMC1 Related Research Area
UIMC1 involved in several pathways and played different roles in them. We selected most pathways UIMC1 participated on our site, such as Cell Cycle, Cell Cycle Checkpoints, DNA Double Strand Break Response, which may be useful for your reference. Also, other proteins which involved in the same pathway with UIMC1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Cell Cycle | ZBTB17;CDKN2A;TSGA14;TUBGCP2;ORC1L;MCM6L;CDC25A;CEP164;RBBP4 |
| Cell Cycle Checkpoints | CLSPN;BRE;DBF4;HIST3H2BB;RAD1;RAD9B;RNF168;KAT5;FAM175A |
| DNA Double Strand Break Response | SMARCA5;UIMC1;BRCC3;RNF168;UBE2V2;HTATIP;RAD50;BARD1;BRE |
| DNA Double-Strand Break Repair | FUZ;PARP2;RAD9A;TDP1;EYA2;RAD1;RNF4;KDM4A;TIMELESS |
| DNA Repair | CLSPN;INO80E;CHD1L;EME1;COPS8;CETN2;RAD1;USP43;ASCC3 |
| G2/M Checkpoints | RAD1;BRE;RAD17;RAD9A;TP53BP1;BRCC3;RAD9B;RNF168;UIMC1 |
| G2/M DNA damage checkpoint | THRSP;UIMC1;BRCC3;RNF168;BRE;TP53BP1;BABAM1;FAM175A;BARD1 |
| HDR through Homologous Recombination (HR) or Single Strand Annealing (SSA) | HUS1;TP53BP1;KIAA0146;EME2;TOPBP1;BRE;PPP4R2B;RNF4;RAD9 |
UIMC1 has several biochemical functions, for example, K63-linked polyubiquitin binding, histone binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by UIMC1 itself. We selected most functions UIMC1 had, and list some proteins which have the same functions with UIMC1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| K63-linked polyubiquitin binding | ATRIP;ZRANB3;ZRANB1B;PRPF8;TAB2;ZRANB1;SPRTN;SQSTM1;RNF168 |
| histone binding | NOC2L;UHRF1;PIH1D1;CHAF1B;DTX3L;HIST1H3I;PRKCBB;NCAPD3;HIST1H4N |
| protein binding | EBF1;TOP1;RASSF1;SKP1;CC10;PPP2R1B;ZNF18;EPN1;NR1H4 |
UIMC1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with UIMC1 here. Most of them are supplied by our site. Hope this information will be useful for your research of UIMC1.
FAM175A; BRCA1; PYCRL; CASK
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