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UPK1A

Official Full Name

uroplakin 1A
Overview

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is found in the asymmetrical unit membrane (AUM) where it can complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions.
Synonyms

UPK1A; uroplakin 1A; uroplakin-1a; TSPAN21; UP1A; UPIA; UPKA; tspan-21; uroplakin Ia; tetraspanin-21;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Bos taurus (Bovine)
Homo sapiens (Human)
Human
Mouse
Mus musculus (Mouse)
Rhesus Macaque
Zebrafish

Source

E.coli
E.coli expression system
HEK293
Mammalian Cell

Tag

His
His (Fc)
Avi
His|T7
N/A
N

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	UPK1A-7920H	Recombinant Human UPK1A protein, His & T7-tagged	E.coli	His/T7	His117~Gly232 (Accession # O00322)	Inquiry
Human	UPK1A-723HCL	Recombinant Human UPK1A lysate	HEK293	N/A		Inquiry
Human	UPK1A-5584H	Recombinant Human UPK1A Protein (His117-Gly232), N-His tagged	E.coli	N-His	His117-Gly232	Inquiry
Mouse	Upk1a-7921M	Recombinant Mouse Upk1a protein, His & T7-tagged	E.coli	His/T7	His116~Gly231 (Accession # Q9D132)	Inquiry
Bos taurus (Bovine)	RFL12149BF	Recombinant Full Length Bovine Uroplakin-1A(Upk1A) Protein, His-Tagged	E.coli expression system	His	Full Length (1-258)	Inquiry
Homo sapiens (Human)	RFL13422HF	Recombinant Full Length Human Uroplakin-1A(Upk1A) Protein, His-Tagged	E.coli expression system	His	Full Length (1-258)	Inquiry
Mus musculus (Mouse)	RFL30194MF	Recombinant Full Length Mouse Uroplakin-1A(Upk1A) Protein, His-Tagged	E.coli expression system	His	Full Length (1-257)	Inquiry
Rhesus Macaque	UPK1A-5109R	Recombinant Rhesus monkey UPK1A Protein, His-tagged	Mammalian Cell	His		Inquiry
Rhesus Macaque	UPK1A-4922R	Recombinant Rhesus Macaque UPK1A Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rhesus Macaque	UPK1A-4922R-B	Recombinant Rhesus Macaque UPK1A Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Zebrafish	UPK1A-3729Z	Recombinant Zebrafish UPK1A	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein

UPK1A involved in several pathways and played different roles in them. We selected most pathways UPK1A participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with UPK1A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

UPK1A has several biochemical functions, for example, monosaccharide binding, protein homodimerization activity. Some of the functions are cooperated with other proteins, some of the functions could acted by UPK1A itself. We selected most functions UPK1A had, and list some proteins which have the same functions with UPK1A. You can find most of the proteins on our site.

Function	Related Protein
monosaccharide binding	RPIA;GPI;GPR19;Siglece;TALDO1;UPK1A;PGLS;FBP1;GPI1
protein homodimerization activity	ANG;ALDH5A1;SLK;CD8A;TRPM8;PYCARD;SETMAR;ADD1;NR4A2

UPK1A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with UPK1A here. Most of them are supplied by our site. Hope this information will be useful for your research of UPK1A.