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UPP2

Official Full Name

uridine phosphorylase 2
Synonyms

UPP2; uridine phosphorylase 2; UDRPASE2; UP2; UPASE2; Liver specific uridine phosphorylase; UPase 2; UPP 2; UPP2_HUMAN; UrdPase 2; uridine phosphorylase-2; liver-specific uridine phosphorylase;

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	UPP2-3604H	Recombinant Human UPP2, GST-tagged	E.coli	GST	1-317aa	$319 / 25ug
Human	UPP2-493HCL	Recombinant Human UPP2 293 Cell Lysate	HEK293	N/A		Inquiry
Mouse	Upp2-1295M	Recombinant Mouse Upp2 protein, His & T7-tagged	E.coli	His/T7	Met1~Ser320 (Accession # Q8CGR7)	Inquiry
Mouse	Upp2-6849M	Recombinant Mouse Upp2 Protein, Myc/DDK-tagged	HEK293T	Myc/DDK		Inquiry
Zebrafish	UPP2-10493Z	Recombinant Zebrafish UPP2	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
UPP2 Related Articles

UPP2 involved in several pathways and played different roles in them. We selected most pathways UPP2 participated on our site, such as Drug metabolism - other enzymes, Fluoropyrimidine Activity, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with UPP2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Drug metabolism - other enzymes	UGT1A1;GUSB;IMPDH1A;UGT5G1;TYMP;IMPDH2;PNAT3;UPP2;UGT1A6
Fluoropyrimidine Activity	DPYD;SLC22A7;DHFR;TYMP;DPYS;CES1;UPP2
Metabolic pathways	GANC;DGKD;PMM2;CYP26A1;ENO1;ACAT2;ASL;HMGCRB;ARG2
Metabolism	AKR1C6;AQP1A.2;ACER1;CHAT;ECI1;NUDT15;CYP3C4;CYP2V1;COX5B
Metabolism of nucleotides	PAICS;NUDT1;PROZA;ADAL;UPP2;DCK;PNP5B;DUT;ADK
Pyrimidine catabolism	UPP2;TYMP;DPYD;PROZA;DPYDA.1;DPYS
Pyrimidine metabolism	POLR2F;NME5;POLA2;POLR2J2;POLR3B;DUT;AK9;POLR2EB;TRR1
Pyrimidine salvage reactions	DCK;UPP2

UPP2 has several biochemical functions, for example, protein binding, uridine phosphorylase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by UPP2 itself. We selected most functions UPP2 had, and list some proteins which have the same functions with UPP2. You can find most of the proteins on our site.

Function	Related Protein
protein binding	C14orf135;STARD13;KCTD13;KIAA1524;NT5C3B;GDF5;PSMA2;CHUK;CXXC1
uridine phosphorylase activity	UPP1;UPP2

UPP2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with UPP2 here. Most of them are supplied by our site. Hope this information will be useful for your research of UPP2.

SIAH1

Ma, GY; Zhang, JZ; et al. Toxoplasma gondii: Proteomic analysis of antigenicity of soluble tachyzoite antigen. EXPERIMENTAL PARASITOLOGY 122:41-46(2009).

Tokunaga, Y; Sasaki, H; et al. Clinical role of orotate phosphoribosyl transferase and dihydropyrimidine dehydrogenase in colorectal cancer treated with postoperative fluoropyrimidine. SURGERY 141:346-353(2007).

Liu, MP; Cao, DL; et al. Expression, characterization, and detection of human uridine phosphorylase and identification of variant uridine phosphorolytic activity in selected human tumors. CANCER RESEARCH 58:5418-5424(1998).