uqcrh
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  • Official Full Name
  • ubiquinol-cytochrome c reductase hinge protein
  • Background
  • Cytochrome b-c1 complex subunit 6, mitochondrial is a protein that in humans is encoded by the UQCRH gene.
  • Synonyms
  • UQCRH; ubiquinol-cytochrome c reductase hinge protein; cytochrome b-c1 complex subunit 6, mitochondrial; QCR6; ubiquinol cytochrome c reductase; complex III subunit VIII; UQCR8; Complex III subunit 6; Cytochrome b c1 complex subunit 6; Cytochrome b c1 complex subunit 6 mitochondrial; Cytochrome c1 non heme 11 kDa protein; MGC111572; Mitochondrial hinge protein; QCR 6; Ubiquinol cytochrome c reductase complex 11 kDa protein; Ubiquinol cytochrome c reductase complex 11 kDa protein mitochondrial; Ubiquinol cytochrome c reductase hinge protein; cytochrome c1 non-heme 11 kDa protein; ubiquinol-cytochrome c reductase complex 11 kDa protein; ubiquinol-cytochrome c reductase, complex III subunit VIII
Cat.#:UQCRH-145HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human UQCRH Protein, GST-tagged
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Cat.#:UQCRH-2457HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant human UQCRH, His-tagged
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Cat.#:UQCRH-3607HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human UQCRH, GST-tagged
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Cat.#:UQCRH-6460RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat UQCRH Protein
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Cat.#:UQCRH-5114RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey UQCRH Protein, His-tagged
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Cat.#:UQCRH-5050CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken UQCRH
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Cat.#:UQCRH-3478ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish UQCRH
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Cat.#:UQCRH-486HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human UQCRH 293 Cell Lysate
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Involved Pathway

UQCRH involved in several pathways and played different roles in them. We selected most pathways UQCRH participated on our site, such as Oxidative phosphorylation, Metabolic pathways, Cardiac muscle contraction, which may be useful for your reference. Also, other proteins which involved in the same pathway with UQCRH were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Oxidative phosphorylation
UQCRB; ATP5O; ATP6V0CB; LHPP; SDHDA; NDUFS4; NDUFS1; SDHC; COX7B2; NDUFB8
Metabolic pathways
CTPS2; ALDH2.2; PIGM; GGT5A; NT5C3L; ALLC; DSE; TH; CYP26A1; PNMT
Cardiac muscle contraction
UQCR10; TPM3; CACNB4A; ATP1B4; CACNG1A; TNNT2A; SLC9A1; TPM4A; MYL3; TPM1
Non-alcoholic fatty liver disease (NAFLD)
CYCS; ADIPOR2; SREBF1; NDUFA11; PRKAG3; NDUFA13; IRS2; NDUFA8; EIF2AK3; NR1H3
Alzheimers disease
BID; NOS1; NDUFAB1; FADD; NDUFA13; PPP3CA; NDUFA8; ATP5C1; COX7B2; COX5A
Parkinsons disease
PARK7; NDUFB6; UBE2G2; NDUFA13; NDUFA6; GNAI2; NDUFS8; SLC25A6; UQCRC1; SEPT5
Huntingtons disease
TBPL2; NDUFC1; SOD1; SOD2; CREB3L1; SIN3A; NDUFA4L2; DNAH5; ATP5E; ATP5J

Protein Function

UQCRH has several biochemical functions, for example, protein binding, ubiquinol-cytochrome-c reductase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by UQCRH itself. We selected most functions UQCRH had, and list some proteins which have the same functions with UQCRH. You can find most of the proteins on our site.
Function
Related Protein
Function protein binding
Related Protein C1R; FYN; PYGB; TLX2; QRICH1; PLA2G16; PSMB5; ANKRD45; PSIP1; MIF4GD
Function ubiquinol-cytochrome-c reductase activity
Related Protein UQCRQ; UQCRC1; UQCRH; UQCRFS1; UQCR11; UQCR10

Interacting Protein

UQCRH has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with UQCRH here. Most of them are supplied by our site. Hope this information will be useful for your research of UQCRH.
ARL8A; FAM189B; RNF24; SIRT3; NPM1; HTT; NDUFA12

UQCRH Related Articles

Berry, EA; De Bari, H; et al. Unanswered questions about the structure of cytochrome bc(1) complexes. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS 1827:1258-1277(2013).
Ye, RS; Pan, HB; et al. Molecular characterization and tissue expression profile of three novel ovine genes: ATP5O, NDUFA12 and UQCRH from muscle full-length cDNA library of black-boned sheep. MOLECULAR BIOLOGY REPORTS 39:5767-5774(2012).