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UROD

  • Official Full Name

    uroporphyrinogen decarboxylase

  • Overview

    Procalcitonin (PCT) is a 116 amino acid residue peptide with molecular weight of about 13 kDa. PCT itself has no known hormonal activity. PCT belongs to a group of related proteins including calcitonin gene-related peptides I and II, amylin, adrenomodulin and calcitonin (CAPA peptide family). PCT, like other peptides of CAPA family, appears from the common precursor pre-procalcitonin consisting of 141 amino acids by removal of 25 amino acids from the N-terminus. PCT undergoes successive cleavages to form three molecules: N-terminal fragment (55 a.a.), calcitonin (32 a.a.) and katacalcin (21 a.a.). Under normal metabolic conditions, PCT is only present in the C cells of the thyroid gland. In bacterial infection and sepsis, however, intact PCT is found in the blood and, more importantly, its level is related to the severity of bacterial sepsis. Today, PCT is considered to be one of the earliest and most specific markers of sepsis.
  • Synonyms

    UROD; uroporphyrinogen decarboxylase; uroporphyrinogen III decarboxylase; PCT; UPD;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • Mammalian Cell
  • GST
  • His
  • His (Fc)
  • Avi
  • Strep
  • Myc
  • DDK
  • N/A
  • N
  • No tag
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human UROD-3608H Recombinant Human UROD, GST-tagged E.coli GST 1-367aa
Human UROD-730H Recombinant Human Uroporphyrinogen Decarboxylase, His-tagged E.coli His
Human UROD-621H Recombinant Human UROD Protein, His-tagged E.coli His
Human UROD-156H Recombinant Human Uroporphyrinogen Decarboxylase, His-tagged E.coli His
Human UROD-483HCL Recombinant Human UROD 293 Cell Lysate HEK293 N/A
Human UROD-3332H Recombinant Human UROD protein, His-GST-tagged E.coli His/GST Ala25~Cys85
Human UROD-0238H Recombinant Human UROD Protein (M1-N367), His/Strep tagged E.coli His/Strep M1-N367
Human UROD-1672H Recombinant Human UROD Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human UROD-0239H Recombinant Human UROD Protein (M1-N367), Tag Free E.coli No tag M1-N367
Mouse UROD-17887M Recombinant Mouse UROD Protein Mammalian Cell His
Mouse Urod-540M Recombinant Mouse Urod Protein, His-tagged E.coli N-His Met1-Asn367
Mouse Urod-6857M Recombinant Mouse Urod Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse UROD-9939M-B Recombinant Mouse UROD Protein Pre-coupled Magnetic Beads HEK293
Mouse UROD-9939M Recombinant Mouse UROD Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat Urod-498R Recombinant Rat Urod Protein, His-tagged E.coli His Asn1~Asn364
Zebrafish UROD-8930Z Recombinant Zebrafish UROD Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

UROD involved in several pathways and played different roles in them. We selected most pathways UROD participated on our site, such as Porphyrin and chlorophyll metabolism, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with UROD were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Porphyrin and chlorophyll metabolismUGT1A9;ALAS2;UGT1A4;UGT2A2;UGT1A6A;FECH;HMOX1A;P22;UGT1A1
Metabolic pathwaysNDUFB6;HSD3B7;B4GALT7;MGAT4A;UQCRQ;GALNTL6;BAAT;ALDH18A1;PAFAH1B3

UROD has several biochemical functions, for example, ferrous iron binding, protein binding, uroporphyrinogen decarboxylase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by UROD itself. We selected most functions UROD had, and list some proteins which have the same functions with UROD. You can find most of the proteins on our site.

Function Related Protein
ferrous iron bindingISCUB;UROD;ALKBH2;EGLN2;SERPINB1A;HAAO;ALKBH1;ISCU;ISCA1
protein bindingKRT6A;CDC42SE2;LBR;SULT1A1;SOD1;KLRC1;TEX13A;SPEF1;NR1H4
uroporphyrinogen decarboxylase activity

UROD has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with UROD here. Most of them are supplied by our site. Hope this information will be useful for your research of UROD.

FAM84B; Urod; EGFR; VIM; pepQ; CHD3; HMGXB4; FAF1

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