urod
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  • Official Full Name
  • uroporphyrinogen decarboxylase
  • Background
  • Procalcitonin (PCT) is a 116 amino acid residue peptide with molecular weight of about 13 kDa. PCT itself has no known hormonal activity. PCT belongs to a group of related proteins including calcitonin gene-related peptides I and II, amylin, adrenomodulin and calcitonin (CAPA peptide family). PCT, like other peptides of CAPA family, appears from the common precursor pre-procalcitonin consisting of 141 amino acids by removal of 25 amino acids from the N-terminus. PCT undergoes successive cleavages to form three molecules: N-terminal fragment (55 a.a.), calcitonin (32 a.a.) and katacalcin (21 a.a.). Under normal metabolic conditions, PCT is only present in the C cells of the thyroid gland. In bacterial infection and sepsis, however, intact PCT is found in the blood and, more importantly, its level is related to the severity of bacterial sepsis. Today, PCT is considered to be one of the earliest and most specific markers of sepsis.
  • Synonyms
  • UROD; uroporphyrinogen decarboxylase; uroporphyrinogen III decarboxylase; PCT; UPD;
Cat.#:Urod-498RTag:His
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Urod Protein, His-tagged
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Cat.#:UROD-3608HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human UROD, GST-tagged
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Cat.#:UROD-621HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human UROD Protein, His-tagged
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Cat.#:UROD-730HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Uroporphyrinogen Decarboxylase, His-tagged
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Cat.#:UROD-17887MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse UROD Protein
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Cat.#:UROD-8930ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish UROD
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Cat.#:UROD-156HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Uroporphyrinogen Decarboxylase, His-tagged
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Cat.#:UROD-483HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human UROD 293 Cell Lysate
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Involved Pathway

UROD involved in several pathways and played different roles in them. We selected most pathways UROD participated on our site, such as Porphyrin and chlorophyll metabolism, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with UROD were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Porphyrin and chlorophyll metabolism
MMAB; HEPH; HCCSB; UGT5G1; UGT1A7; UGT1A6A; UROD; ALAS2; UGT1A9; COX15
Metabolic pathways
ALDH1A1; MIBP; C1GALT1C1; EXT1A; MTMR7A; BCO1L; ATP5H; CBR2; PAFAH1B1A; NDUFAB1

Protein Function

UROD has several biochemical functions, for example, ferrous iron binding, protein binding, uroporphyrinogen decarboxylase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by UROD itself. We selected most functions UROD had, and list some proteins which have the same functions with UROD. You can find most of the proteins on our site.
Function
Related Protein
Function ferrous iron binding
Related Protein TET2; ALKBH3; BCO1; FTO; ACP5; ALKBH2; Trf; CDO1; SNCA; TRR1
Function protein binding
Related Protein MOB1A; CCDC141; FAM110A; PTCRA; PACSIN2; UGP2; PPP1R1A; RBM17; ZNF670; ADAR
Function uroporphyrinogen decarboxylase activity
Related Protein UROD

Interacting Protein

UROD has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with UROD here. Most of them are supplied by our site. Hope this information will be useful for your research of UROD.
FAM84B; Urod; EGFR; VIM; pepQ; CHD3; HMGXB4; FAF1