ush1c
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  • Official Full Name
  • Usher syndrome 1C (autosomal recessive, severe)
  • Background
  • This gene encodes a scaffold protein that functions in the assembly of Usher protein complexes. The protein contains PDZ domains, a coiled-coil region with a bipartite nuclear localization signal and a PEST degradation sequence. Defects in this gene are the cause of Usher syndrome type 1C and non-syndromic sensorineural deafness autosomal recessive type 18. Multiple transcript variants encoding different isoforms have been found for this gene.
  • Synonyms
  • USH1C; Usher syndrome 1C (autosomal recessive, severe); deafness, autosomal recessive 18 , DFNB18; harmonin; AIE 75; NY CO 37; NY CO 38; PDZ 73; PDZ73; antigen NY-CO-38/NY-CO-37; usher syndrome type-1C protein; renal carcinoma antigen NY-REN-3; autoimmune
Cat.#:USH1C-29610THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human USH1C, His-tagged
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Cat.#:USH1C-29611THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human USH1C, His-tagged
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Cat.#:USH1C-3610HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human USH1C, GST-tagged
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Cat.#:USH1C-3847HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human USH1C, His tagged
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Cat.#:USH1C-475HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Usher Syndrome 1C, His-tagged
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Cat.#:USH1C-3685ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish USH1C
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Cat.#:USH1C-1892HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human USH1C cell lysate
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Protein Function

USH1C has several biochemical functions, for example, actin filament binding, myosin tail binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by USH1C itself. We selected most functions USH1C had, and list some proteins which have the same functions with USH1C. You can find most of the proteins on our site.
Function
Related Protein
Function actin filament binding
Related Protein MTSS1; SHROOM1; WIPF2B; TMOD1; ACTN2B; LIMA1; MYH9A; SVILA; CORO6; EGFR
Function myosin tail binding
Related Protein USH1C
Function protein binding
Related Protein DDOST; P4HA1; CYB561; GPR158; FBXL8; SMARCC2; TMSB10; PLEKHN1; MTMR9; FLOT2
Function spectrin binding
Related Protein ADD2; USH1C; STX4A; DYNC1I1; USH1G; DCTN2; GBP1; CAMSAP1; MYO7A; KIF3A

Interacting Protein

USH1C has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with USH1C here. Most of them are supplied by our site. Hope this information will be useful for your research of USH1C.
RAC1; MIPOL1; CTNNAL1; USHBP1; QKI; pi3p; USH1G; CDHR2

USH1C Related Articles

Lampasona, V; Passerini, L; et al. Autoantibodies to Harmonin and Villin Are Diagnostic Markers in Children with IPEX Syndrome. PLOS ONE 8:-(2013).
Zhao, HY; Avenarius, MR; et al. Improved Biolistic Transfection of Hair Cells. PLOS ONE 7:-(2012).