UTS2
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Official Full Name
urotensin 2
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Overview
This gene encodes a mature peptide that is an active cyclic heptapeptide absolutely conserved from lamprey to human. The active peptide acts as a vasoconstrictor and is expressed only in brain tissue. Despite the gene family name similarity, this gene is not homologous to urocortin, a member of the sauvagine/corticotropin-releasing factor/urotensin I family. Most of the proprotein is cleaved to make the mature peptide. Transcript variants encoding different preproprotein isoforms have been described for this gene. -
Synonyms
UTS2; UTS2 urotensin 2 [ Homo sapiens ]; UII; U-II; UCN2; PRO1068; urotensin-2; urotensin 2; Urotensin II; OTTHUMP00000001356;
- Recombinant Proteins
- Protein Pre-coupled Magnetic Beads
- Chicken
- Human
- Rat
- Rhesus Macaque
- E.coli
- HEK293
- Mammalian Cell
- His
- His (Fc)
- Avi
- N
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | UTS2-51H | Recombinant Human UTS2 protein, His-tagged | E.coli | His |
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| Human | UTS2-506H | Recombinant Human UTS2 Protein, His-tagged | E.coli | His | Ser20~Trp120 |
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| Human | UTS2-5572H | Recombinant Human UTS2 Protein (Pro36-Val124), N-His tagged | E.coli | N-His | Pro36-Val124 |
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| Rat | UTS2-6483R | Recombinant Rat UTS2 Protein | Mammalian Cell | His |
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| Rat | UTS2-6139R-B | Recombinant Rat UTS2 Protein Pre-coupled Magnetic Beads | HEK293 |
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| Rat | UTS2-6139R | Recombinant Rat UTS2 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
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| Rhesus Macaque | UTS2-5137R | Recombinant Rhesus monkey UTS2 Protein, His-tagged | Mammalian Cell | His |
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| Rhesus Macaque | UTS2-4950R-B | Recombinant Rhesus Macaque UTS2 Protein Pre-coupled Magnetic Beads | HEK293 |
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| Rhesus Macaque | UTS2-4950R | Recombinant Rhesus Macaque UTS2 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
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| Chicken | UTS2-7113C | Recombinant Chicken UTS2 | Mammalian Cell | His |
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- Involved Pathway
- Protein Function
- Interacting Protein
- UTS2 Related Research Area
UTS2 involved in several pathways and played different roles in them. We selected most pathways UTS2 participated on our site, such as Class A/1 (Rhodopsin-like receptors), G alpha (q) signalling events, GPCR downstream signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with UTS2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Class A/1 (Rhodopsin-like receptors) | SST1.1;GPR31;CCR8;ADRA1D;CHRM4;EDN1;HCAR1-2;ANXA1;PNOC |
| G alpha (q) signalling events | DGKG;KISS1;NMUR1;ANXA1C;RGS18;TRPC6A;EDNRAB;ANXA1A;RGS21 |
| GPCR downstream signaling | TIAM2;HCAR1-2;TRH;CXCL13;FPR-RS4;RHOGA;PROK1;CCR6;AKAP13 |
| GPCR ligand binding | TAC1;RAMP3;S1PR5B;LPAR2B;HCRT;PENKB;TRH;OPN1SW;CALCA |
| Gastrin-CREB signalling pathway via PKC and MAPK | LTB4R;ANXA1C;TAC1;UTS2D;PRKCHB;DGKB;PROK2;MGLL;PMCH |
| Peptide ligand-binding receptors | NPB;RXFP2;INSL5;NMBA;EDN3;PMCH;CCRL2;TAC1;PROK1 |
| Signal Transduction | SRY;RBP1;GRAP;RTN4;CDH5;APOA4A;NOG1;OR56A1;RSPO2 |
| Signaling by GPCR | PRKCHB;OR52B4;CRHB;EMR3;SCT;EMR4;PENKB;ZFPM2B;XK |
UTS2 has several biochemical functions, for example, hormone activity, receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by UTS2 itself. We selected most functions UTS2 had, and list some proteins which have the same functions with UTS2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| hormone activity | INHBAB;PRL8A8;CSHL1;INSL4;IFNT2;PRL4A1;INHBA;APLN;NPPB |
| receptor binding | ALCAM;SNX17;FGF8B;KCNJ10;CAPRIN2;PTK6B;VTCN1;DIAPH1;MAG |
UTS2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with UTS2 here. Most of them are supplied by our site. Hope this information will be useful for your research of UTS2.
- Q&As
- Reviews
Q&As (5)
Ask a questionPotential side effects of UTS2 protein modulation may include changes in blood pressure, cardiovascular function, and renal function.
Some studies have suggested that UTS2 protein expression may be associated with cancer prognosis and could potentially serve as a prognostic marker in certain types of cancer.
Research suggests that UTS2 protein levels may serve as a potential biomarker for cardiovascular diseases and may have diagnostic or prognostic value.
UTS2 protein and its receptors have been investigated as potential targets for the development of novel treatments for cardiovascular diseases.
Clinical trials investigating the use of UTS2 protein antagonists or inhibitors in cancer therapy are currently underway.
Customer Reviews (3)
Write a reviewIts exceptional purity and functionality make it an ideal choice for accurate and precise analysis, ensuring reliable and reproducible results.
By incorporating the UTS2 Protein into their studies, scientists can confidently conduct their research, ushering in groundbreaking discoveries and novel insights within their respective domains.
Its purity and efficacy make it an ideal choice for precise and accurate analysis, allowing me to generate reliable results.
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