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Uxt

Official Full Name

ubiquitously-expressed, prefoldin-like chaperone
Overview

The protein encoded by this gene functions as a cofactor that modulates androgen receptor-dependent transcription, and also plays a critical role in tumor necrosis factor-induced apoptosis. Expression of this gene may play a role in tumorigenesis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Synonyms

STAP1; ART-27; ubiquitously-expressed, prefoldin-like chaperone; UXT;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse
Rat
Zebrafish

Source

E.coli
HEK293
HEK293T
Mammalian Cell

Tag

GST
His
His (Fc)
Avi
His|T7
Myc
DDK
N/A
N

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	UXT-3639H	Recombinant Human UXT, GST-tagged	E.coli	GST	1-157aa	$319 / 25ug
Human	UXT-7926H	Recombinant Human UXT protein, His & T7-tagged	E.coli	His/T7	Glu15~His157 (Accession # Q9UBK9)	Inquiry
Human	UXT-442HCL	Recombinant Human UXT 293 Cell Lysate	HEK293	N/A		Inquiry
Human	UXT-6629H	Recombinant Human UXT Protein (Glu15-His157), N-His tagged	E.coli	N-His	Glu15-His157	Inquiry
Human	UXT-2890H	Recombinant Human UXT Protein, Myc/DDK-tagged, C13 and N15-labeled	HEK293T	Myc/DDK		Inquiry
Mouse	Uxt-7927M	Recombinant Mouse Uxt protein, His & T7-tagged	E.coli	His/T7	Asp11~His157 (Accession # Q9WTZ0)	Inquiry
Mouse	Uxt-6889M	Recombinant Mouse Uxt Protein, Myc/DDK-tagged	HEK293T	Myc/DDK		Inquiry
Rat	UXT-6488R	Recombinant Rat UXT Protein	Mammalian Cell	His		Inquiry
Rat	UXT-6144R	Recombinant Rat UXT Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rat	UXT-6144R-B	Recombinant Rat UXT Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Zebrafish	UXT-1380Z	Recombinant Zebrafish UXT	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein

Uxt involved in several pathways and played different roles in them. We selected most pathways Uxt participated on our site, such as E2F transcription factor network, which may be useful for your reference. Also, other proteins which involved in the same pathway with Uxt were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
E2F transcription factor network	CBX5;E2F6;TRIM28;HIC1;RYBP;CEBPA;SMARCA2;RBBP8;CDKN2C

Uxt has several biochemical functions, for example, RNA polymerase II transcription corepressor activity, NOT actin filament binding, beta-tubulin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Uxt itself. We selected most functions Uxt had, and list some proteins which have the same functions with Uxt. You can find most of the proteins on our site.

Function	Related Protein
RNA polymerase II transcription corepressor activity	HDAC1;RBBP8;TBX18;UXT;HEYL;HDGF;BEND6;TLE1;SIN3A
NOT actin filament binding	MAP1S;UXT;LRPPRC
beta-tubulin binding	ARL8A;NDEL1;PDCD5;PIFO;RANBP10;UXT;SPAST;SERPINB1A;B4GALT1
chromatin binding	TAL1;TTC5;UBTF;MNT;FANCM;WAC;ARID5A;ASF1A;NKX2
microtubule binding	PRC1;MAP2;PRNP;KATNA1;LRPPRC;KIF6;PAFAH1B1A;KIF18A;NPSNL
protein binding	EXO1;NFYA;TMEM86B;INSR;TXNDC16;ATP11C;SMARCAD1;CC2D1B;MID1

Uxt has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Uxt here. Most of them are supplied by our site. Hope this information will be useful for your research of Uxt.

RELA; MECOM; KRTAP10-7; KRTAP10-8; KRT31; KRT40