vangl1
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  • Official Full Name
  • vang-like 1 (van gogh, Drosophila)
  • Background
  • This gene encodes a member of the tretraspanin family. The encoded protein may be involved in mediating intestinal trefoil factor induced wound healing in the intestinal mucosa. Mutations in this gene are associated with neural tube defects. Alternate splicing results in multiple transcript variants.
  • Synonyms
  • VANGL1; vang-like 1 (van gogh, Drosophila); vang (van gogh, Drosophila) like 1, vang, van gogh like 1 (Drosophila); vang-like protein 1; STB2; Loop tail protein 2 homolog; LPP2; MGC5338; STBM2; Strabismus 2; Van Gogh like protein 1; Vang like 1 (van gogh, Drosophila); Vang like protein 1; VANGL 1; OTTHUMP00000013750; OTTHUMP00000013751; OTTHUMP00000013752; van Gogh-like protein 1; loop-tail protein 2 homolog; KAI1 C-terminal interacting tetraspanin; KITENIN
Cat.#:VANGL1-3643HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human VANGL1, GST-tagged
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Cat.#:Vangl1-1483MTag:His/T7
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Vangl1 protein, His & T7-tagged
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Cat.#:VANGL1-11765ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish VANGL1
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Cat.#:VANGL1-433HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human VANGL1 293 Cell Lysate
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Involved Pathway

VANGL1 involved in several pathways and played different roles in them. We selected most pathways VANGL1 participated on our site, such as Wnt signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with VANGL1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Wnt signaling pathway
GPC4; AXIN2; RHOAD; DVL3A; FZD7; RAC3B; PRKACAA; SMAD3; WNT1; MMP7

Protein Function

VANGL1 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by VANGL1 itself. We selected most functions VANGL1 had, and list some proteins which have the same functions with VANGL1. You can find most of the proteins on our site.
Function
Related Protein
Function protein binding
Related Protein NUMBL; TMEM59; NPBWR2; ALS2; DCSTAMP; RHEB; CALU; EXOC3; KIAA1737; MUC2

Interacting Protein

VANGL1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with VANGL1 here. Most of them are supplied by our site. Hope this information will be useful for your research of VANGL1.
CD82; SRPK1; GMFG; RAPGEF5; NT5C3A; THAP2; SMYD3; RASSF10; RASSF9; NAF1; EPB41L3