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VCX3A

Official Full Name

variable charge, X-linked 3A
Overview

This gene belongs to the VCX/Y gene family, which has multiple members on both X and Y chromosomes, and all are expressed exclusively in male germ cells. The X-linked members are clustered on chromosome Xp22 and Y-linked members are two identical copies of the gene within a palindromic region on Yq11. The family members share a high degree of sequence identity, with the exception that a 30-bp unit is tandemly repeated in X-linked members but occurs only once in Y-linked members. The VCX gene cluster is polymorphic in terms of copy number; different individuals may have a different number of VCX genes. VCX/Y genes encode small and highly charged proteins of unknown function. The presence of a putative bipartite nuclear localization signal suggests that VCX/Y members are nuclear proteins. This gene contains 8 repeats of the 30-bp unit.
Synonyms

VCX3A; variable charge, X-linked 3A; variable charge, X linked 3 , VCX3; variable charge X-linked protein 3; VCX 8r; VCX A; MGC118976; MGC125730; MGC125796; Variable charge protein on X with eight repeats; Variable charge X linked 3A; Variable charge X linked protein 3; Variably charged protein X A; Variably charged X A; VCX 3; VCX 3A; VCX3; VCX8R; VCXA; OTTHUMP00000022866; variably charged X-A; variably charged protein X-A; VCX-A; VCX-8r;

Species	Cat.#	Product name	Source (Host)	Tag	Price
Human	VCX3A-1903HCL	Recombinant Human VCX3A cell lysate		N/A	Inquiry
Human	VCX3A-103H	Recombinant Human VCX3A Protein, MYC/DDK-tagged	HEK293	Myc/DDK	Inquiry
Human	VCX3A-1533H	Recombinant Human VCX3A Protein, Myc/DDK-tagged, C13 and N15-labeled	HEK293T	Myc/DDK	Inquiry

VCX3A Related Articles

VCX3A involved in several pathways and played different roles in them. We selected most pathways VCX3A participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with VCX3A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

VCX3A has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by VCX3A itself. We selected most functions VCX3A had, and list some proteins which have the same functions with VCX3A. You can find most of the proteins on our site.

Function	Related Protein

VCX3A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with VCX3A here. Most of them are supplied by our site. Hope this information will be useful for your research of VCX3A.

Taguchi, A; Taylor, AD; et al. A Search for Novel Cancer/Testis Antigens in Lung Cancer Identifies VCX/Y Genes, Expanding the Repertoire of Potential Immunotherapeutic Targets. CANCER RESEARCH 74:4694-4705(2014).

Ben Khelifa, H; Soyah, N; et al. Xp22.3 interstitial deletion: A recognizable chromosomal abnormality encompassing VCX3A and STS genes in a patient with X-linked ichthyosis and mental retardation. GENE 527:578-583(2013).