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VEZT

  • Official Full Name

    vezatin, adherens junctions transmembrane protein

  • Overview

    This gene encodes a transmembrane protein which has been localized to adherens junctions and shown to bind to myosin VIIA. Examination of expression of this gene in gastric cancer tissues have shown that expression is decreased which appears to be related to hypermethylation of the promoter. Expression of this gene may also be inhibited by binding of a specific microRNA to a target sequence in the 3 UTR of the transcripts. A pseudogene of this gene is located on the X chromosome. Alternative splicing results in multiple transcript variants.
  • Synonyms

    VEZT; vezatin, adherens junctions transmembrane protein; vezatin; DKFZP761C241;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Homo sapiens (Human)
  • Human
  • Mouse
  • Mus musculus (Mouse)
  • Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
  • Rat
  • Rattus norvegicus (Rat)
  • Rhesus Macaque
  • Xenopus laevis (African clawed frog)
  • Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
  • E.coli
  • E.coli expression system
  • HEK293
  • HEK293T
  • Mammalian Cell
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • Myc|DDK
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human VEZT-371H Recombinant Human VEZT Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human VEZT-2945H Recombinant Human VEZT Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human VEZT-2457H Recombinant Human VEZT protein, His-tagged E.coli His 382-731 aa
Mouse VEZT-18009M Recombinant Mouse VEZT Protein Mammalian Cell His
Mouse Vezt-6918M Recombinant Mouse Vezt Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse VEZT-10011M-B Recombinant Mouse VEZT Protein Pre-coupled Magnetic Beads HEK293
Mouse VEZT-10011M Recombinant Mouse VEZT Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat VEZT-6519R Recombinant Rat VEZT Protein Mammalian Cell His
Rat VEZT-6175R-B Recombinant Rat VEZT Protein Pre-coupled Magnetic Beads HEK293
Rat VEZT-6175R Recombinant Rat VEZT Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Homo sapiens (Human) RFL9651HF Recombinant Full Length Human Vezatin(Vezt) Protein, His-Tagged E.coli expression system His Full Length (1-779)
Mus musculus (Mouse) RFL18681MF Recombinant Full Length Mouse Vezatin(Vezt) Protein, His-Tagged E.coli expression system His Full Length (1-780)
Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) RFL35062PF Recombinant Full Length Pongo Abelii Vezatin(Vezt) Protein, His-Tagged E.coli expression system His Full Length (1-731)
Rattus norvegicus (Rat) RFL30950RF Recombinant Full Length Rat Vezatin(Vezt) Protein, His-Tagged E.coli expression system His Full Length (1-782)
Rhesus Macaque VEZT-5154R Recombinant Rhesus monkey VEZT Protein, His-tagged Mammalian Cell His
Rhesus Macaque VEZT-4967R-B Recombinant Rhesus Macaque VEZT Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque VEZT-4967R Recombinant Rhesus Macaque VEZT Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Xenopus laevis (African clawed frog) RFL12848XF Recombinant Full Length Xenopus Laevis Vezatin(Vezt) Protein, His-Tagged E.coli expression system His Full Length (1-774)
Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) RFL19512XF Recombinant Full Length Xenopus Tropicalis Vezatin(Vezt) Protein, His-Tagged E.coli expression system His Full Length (1-791)
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • VEZT Related Articles

VEZT involved in several pathways and played different roles in them. We selected most pathways VEZT participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with VEZT were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

VEZT has several biochemical functions, for example, myosin binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by VEZT itself. We selected most functions VEZT had, and list some proteins which have the same functions with VEZT. You can find most of the proteins on our site.

Function Related Protein
myosin bindingARFGEF1;VETZ;TRIM32;RHOA;DMD;SLC6A4;KIRREL;GIPC1;CALD1B
protein bindingFOXN3;EIF2AK3;GSN;ARL16;PHB2;ACY1;MTERF;ATF4;SIX1

VEZT has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with VEZT here. Most of them are supplied by our site. Hope this information will be useful for your research of VEZT.

Miao, RZ; Guo, XB; et al. VEZT, a Novel Putative Tumor Suppressor, Suppresses the Growth and Tumorigenicity of Gastric Cancer. PLOS ONE 8:-(2013).
Bahloul, A; Simmler, MC; et al. Vezatin, an integral membrane protein of adherens junctions, is required for the sound resilience of cochlear hair cells. EMBO MOLECULAR MEDICINE 1:125-138(2009).
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