WDR5
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Official Full Name
WD repeat domain 5
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Overview
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 7 WD repeats. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008] -
Synonyms
WDR5; WD repeat domain 5; SWD3; BIG-3; WD repeat-containing protein 5; WD-repeat protein 5; BMP2-induced 3-kb gene protein; SWD3, Set1c WD40 repeat protein, homolog;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Others
- Chicken
- Human
- Mouse
- Rat
- Zebrafish
- E.coli
- HEK293
- HEK293T
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- SUMO
- MYC
- DDK
- N/A
- N
- WDR5 Related Research Area
WDR5 involved in several pathways and played different roles in them. We selected most pathways WDR5 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with WDR5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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WDR5 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by WDR5 itself. We selected most functions WDR5 had, and list some proteins which have the same functions with WDR5. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
WDR5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with WDR5 here. Most of them are supplied by our site. Hope this information will be useful for your research of WDR5.
- Q&As
- Reviews
Q&As (5)
Ask a questionYes, WDR5 has been associated with neurodevelopmental disorders, suggesting a role in non-cancerous diseases as well.
WDR5 regulates the expression of genes critical for neural development, and dysregulation can lead to developmental disorders.
Elevated levels of WDR5 in certain cancers can serve as a diagnostic marker when detected in patient samples.
Yes, there are ongoing clinical trials to test the safety and efficacy of WDR5-targeted therapies in cancer patients.
Some studies suggest a potential link between WDR5 and autoimmune diseases, but further research is needed to confirm this association.
Customer Reviews (3)
Write a reviewTheir ability to accommodate the requirements of large-scale experiments and guarantee a reliable supply streamlines my research operations, eliminating any concerns related to potential shortages.
I am confident that the protein will reliably perform in my assays, providing accurate and reproducible results.
the manufacturer's supply management capabilities assure a seamless and continuous provision of the WDR5 protein.
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