wipf1
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  • Official Full Name
  • WAS/WASL interacting protein family, member 1
  • Background
  • May have direct activity on the actin cytoskeleton. Induces actin polymerization and redistribution. Contributes with NCK1 and GRB2 in the recruitment and activation of WASL. May participate in regulating the subcellular localization of WASL, resulting in the disassembly of stress fibers in favor of filopodia formation (By similarity). Plays an important role in the intracellular motility of vaccinia virus by functioning as an adapter for recruiting WASL to vaccinia virus.
  • Synonyms
  • D2Ertd120e; Protein PRPL-2; PRPL 2; PRPL-2 protein; WAS/WASL interacting protein family member 1; WASP-interacting protein; WASPIP; WIP; Wipf1; WIPF1; Wiskott-Aldrich syndrome protein interacting protein; WAS/WASL interacting protein family, member 1
Cat.#:WIPF1-3731HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human WIPF1, His-tagged
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Cat.#:WIPF1-6591RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat WIPF1 Protein
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Cat.#:WIPF1-2132CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken WIPF1
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Cat.#:WIPF1-311HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human WIPF1 293 Cell Lysate
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Involved Pathway

Wipf1 involved in several pathways and played different roles in them. We selected most pathways Wipf1 participated on our site, such as Endocytosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with Wipf1 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Endocytosis
ARPC4L; PIP5K1BB; EEA1; EHD1A; FGFR2; CHMP6B; DNM3; HSPA1A; WIPF1; KITA

Protein Function

Wipf1 has several biochemical functions, for example, actin binding, actin filament binding, profilin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Wipf1 itself. We selected most functions Wipf1 had, and list some proteins which have the same functions with Wipf1. You can find most of the proteins on our site.
Function
Related Protein
Function actin binding
Related Protein MTAP1A; MYHZ1.2; MYH6; MSRB1A; MSRB2; EPS8L2; WASB; CNN3A; TWF2B; GBP1
Function actin filament binding
Related Protein FMNL1; TLN1; TULP1; PLDN; CORO1B; MTSS1; FSCN2A; MARCKS; SYNE2; PLS1
Function profilin binding
Related Protein CYFIP1; FMNL1; DIAP1; WIPF1; HTT; VASP; PCLO; RHOQ; CTTN; DIAPH1
Function protein binding
Related Protein CAMK2G; ZNF649; CCDC24; BIN3; ZBTB25; DYDC1; RAB9B; RTN3; CRTC1; HEATR5B

Interacting Protein

Wipf1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Wipf1 here. Most of them are supplied by our site. Hope this information will be useful for your research of Wipf1.
WAS; WASL