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XAF1

  • Official Full Name

    XIAP associated factor 1

  • Overview

    This gene encodes a protein which binds to and counteracts the inhibitory effect of a member of the IAP (inhibitor of;apoptosis) protein family. IAP proteins bind to and inhibit caspases which are activated during apoptosis. The;proportion of IAPs and proteins which interfere with their activity, such as the encoded protein, affect the progress;of the apoptosis signaling pathway. Multiple transcript variants encoding different isoforms have been found for this;gene.
  • Synonyms

    XAF1; XIAP associated factor 1; XIAP-associated factor 1; BIRC4BP; HSXIAPAF1; XIAPAF1; BIRC4 binding protein; BIRC4-binding protein;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rhesus Macaque
  • E.coli
  • HEK293
  • Mammalian Cell
  • Wheat Germ
  • GST
  • GST|His
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human XAF1-227H Recombinant Human XAF1 Protein, GST-tagged Wheat Germ GST
Human XAF1-185H Recombinant Human XAF1, His-tagged E.coli His 1- 125aa
Human XAF1-271HCL Recombinant Human XAF1 293 Cell Lysate HEK293 N/A
Human XAF1-225H Recombinant Human XAF1 Protein, GST/His-tagged E.coli GST/His
Mouse XAF1-18600M Recombinant Mouse XAF1 Protein Mammalian Cell His
Mouse XAF1-10219M-B Recombinant Mouse XAF1 Protein Pre-coupled Magnetic Beads HEK293
Mouse XAF1-10219M Recombinant Mouse XAF1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque XAF1-5226R Recombinant Rhesus monkey XAF1 Protein, His-tagged Mammalian Cell His
Rhesus Macaque XAF1-5039R Recombinant Rhesus Macaque XAF1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque XAF1-5039R-B Recombinant Rhesus Macaque XAF1 Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • XAF1 Related Articles

XAF1 involved in several pathways and played different roles in them. We selected most pathways XAF1 participated on our site, such as Cytokine Signaling in Immune system, Immune System, Interferon Signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with XAF1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Cytokine Signaling in Immune systemSPRED1;DPF1;NEFLB;MAP3K8;NUP35;PEA15A;IFI35;DUSP9;CASPBL
Immune SystemEDAR;SIGLEC5;UBE2U;SIGLEC7;MGC174857;ACTR1B;MB21D1;DYNC1LI2;TNFRSF13C
Interferon SignalingTRIM5;XAF1;TRIM48;TRIM22;IFI30;IFI27;EIF4E3;GBP4;IFIT10
Interferon alpha/beta signalingIFIT2;IFITM2;USP18;OASL;IFI27;IFI6;ISG20;IRF4;XAF1

XAF1 has several biochemical functions, for example, zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by XAF1 itself. We selected most functions XAF1 had, and list some proteins which have the same functions with XAF1. You can find most of the proteins on our site.

Function Related Protein
zinc ion bindingRNF214;SF3A2;ESRRGA;PIAS1;ZNRD1;RAI1;EHMT1B;RCHY1;RAG1

XAF1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with XAF1 here. Most of them are supplied by our site. Hope this information will be useful for your research of XAF1.

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Long, XG; Li, Y; et al. XAF1 contributes to dengue virus-induced apoptosis in vascular endothelial cells. FASEB JOURNAL 27:1062-1073(2013).
Serrano-Fernandez, P; Moller, S; et al. Time course transcriptomics of IFNB1b drug therapy in multiple sclerosis. AUTOIMMUNITY 43:172-178(2010).
  • Q&As
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