XYLT1
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Official Full Name
xylosyltransferase I
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Overview
This locus encodes a xylosyltransferase enzyme. The encoded protein catalyzes transfer of UDP-xylose to serine residues of an acceptor protein substrate. This transfer reaction is necessary for biosynthesis of glycosaminoglycan chains. Mutations in this gene have been associated with increased severity of pseudoxanthoma elasticum. -
Synonyms
XYLT1; xylosyltransferase I; xylosyltransferase 1; protein xylosyltransferase 1; PXYLT1; XT I; xylT-I; O-xylosyltransferase 1; xylosyltransferase iota; beta-D-xylosyltransferase 1; peptide O-xylosyltransferase 1; XT1; XTI; XT-I; XYLTI;
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | XYLT1-6264H | Recombinant Human XYLT1 Protein (Gly773-Val910), N-His tagged | E.coli | N-His | Gly773-Val910 |
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| Human | XYLT1-1709H | Recombinant Human XYLT1 protein, His & T7-tagged | E.coli | His/T7 | Gly773~Val910 (Accession # Q86Y38) |
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| Mouse | Xylt1-1710M | Recombinant Mouse Xylt1 protein, His & T7-tagged | E.coli | His/T7 | Lys716~Gly954 (Accession # Q811B1) |
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| Zebrafish | XYLT1-7678Z | Recombinant Zebrafish XYLT1 | Mammalian Cell | His |
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- Involved Pathway
- Protein Function
- Interacting Protein
- XYLT1 Related Articles
XYLT1 involved in several pathways and played different roles in them. We selected most pathways XYLT1 participated on our site, such as Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate, Glycosaminoglycan biosynthesis - heparan sulfate / heparin, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with XYLT1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate | CHST3;XYLT2;B3GALT6;CHPF2;CHST12;CHST3B;CHST15;CHST7;CSGALNACT2 |
| Glycosaminoglycan biosynthesis - heparan sulfate / heparin | MAPK1IP1L;GLCEA;HS6ST3;NDST3;XYLT1;EXT1B;HS3ST1;HS6ST1B;EXT1A |
| Metabolic pathways | PPT1;IDUA;GLULA;AGMAT;ACAD8;NOS3;GALNT13;INPP4AB;UQCRC2A |
XYLT1 has several biochemical functions, for example, acetylglucosaminyltransferase activity, protein xylosyltransferase activity, transferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by XYLT1 itself. We selected most functions XYLT1 had, and list some proteins which have the same functions with XYLT1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| acetylglucosaminyltransferase activity | GLT8D1;MGAT1A;C3orf39;A4GNT;DPY19L1;4931440L10Rik;POMGNT2;HEXB;EXT1 |
| protein xylosyltransferase activity | POGLUT1;XYLT1;XYLT2 |
| transferase activity | SULT2ST3;DNMT3AB;STK35L;UGT2A4;PDK2B;ST3GAL2L;ELOVL4;ELOVL7A;REV3L |
XYLT1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with XYLT1 here. Most of them are supplied by our site. Hope this information will be useful for your research of XYLT1.
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