Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953 Learn More

ZNRF3

Official Full Name

zinc and ring finger 3
Synonyms

ZNRF3;zinc and ring finger 3;18126;ENSG00000183579;RNF203;BK747E2.3;22q12.1;E3 ubiquitin-protein ligase ZNRF3;E3 ubiquitin-protein ligase ZNRF3;RING finger protein 203;zinc/RING finger protein 3;novel C3HC4 type Zinc finger (ring finger);EC 6.3.2.-;

Type

Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse

Source

E.coli
HEK293
Insect Cell
Mammalian Cell

Tag

His
His (Fc)
Avi
His|SUMO
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	ZNRF3-4636H	Recombinant Human ZNRF3 protein	E.coli	N/A	56-219aa	Inquiry
Human	ZNRF3-1910H	Recombinant Human ZNRF3 Protein (56-219 aa), His-SUMO-tagged	E.coli	His/SUMO	56-219 aa	Inquiry
Human	ZNRF3-1524H	Recombinant Human ZNRF3 protein, His-tagged	Insect Cell	His	56-219aa	Inquiry
Human	ZNRF3-2111H	Active Recombinant Human ZNRF3 protein, His-tagged	HEK293	His	Lys 56 - Met 219	Inquiry
Mouse	ZNRF3-19221M	Recombinant Mouse ZNRF3 Protein	Mammalian Cell	His		Inquiry
Mouse	ZNRF3-10493M-B	Recombinant Mouse ZNRF3 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Mouse	ZNRF3-10493M	Recombinant Mouse ZNRF3 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry

Involved Pathway
Protein Function
Interacting Protein
ZNRF3 Related Articles
ZNRF3 Related Research Area

ZNRF3 involved in several pathways and played different roles in them. We selected most pathways ZNRF3 participated on our site, such as Regulation of FZD by ubiquitination, Signal Transduction, Signaling by Wnt, which may be useful for your reference. Also, other proteins which involved in the same pathway with ZNRF3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Regulation of FZD by ubiquitination	RNF43;LGR6;RSPO4;LGR5;RSPO3;FMNL3;LGR4;RSPO2;RSPO1
Signal Transduction	CNR2;GPR39;OPN4A;TAC2;CHN1;EVC;TULP3;MDKB;OBSCN
Signaling by Wnt	WIF1;LGR5;DACT1;PYGO2;HECW1;CBY1;SOX4A;HECW1B;SOX6
TCF dependent signaling in response to WNT	SOX7;SOX32;SOX4B;CBY1;LGR6;CCDC88C;SOX13;CDC73;TLE3B

ZNRF3 has several biochemical functions, for example, UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity, coenzyme F420-0 gamma-glutamyl ligase activity, coenzyme F420-2 alpha-glutamyl ligase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ZNRF3 itself. We selected most functions ZNRF3 had, and list some proteins which have the same functions with ZNRF3. You can find most of the proteins on our site.

Function	Related Protein
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity	TRIM41;HECW2;RFWD2;TMEM129;RC3H2;RNF169;SIAH2L;LTN1;RNF144AA
coenzyme F420-0 gamma-glutamyl ligase activity	RAG1;ZNRF3;MARCH5L;MYLIPA;RNF169;TRIM71;UBE2IB;MARCH4;RNF187
coenzyme F420-2 alpha-glutamyl ligase activity	UBE2IB;RC3H2;ZNRF3;HECW2;MARCH4;RNF149;RNF180;MGRN1A;MARCH11
frizzled binding	WNT6;DVL3A;WNT7AA;WNT4A;NDP;FZD1;DVL2;WNT4;RNF43
ligase activity	RTCD1;TTLL6;ZSWIM2;STUB1;TRIM11;DZIP3;SIAH1A;TRIM21;TRIM8
metal ion binding	GALNT18A;ZNF785;NUDT17;ZNF599;COQ7;RBM4.1;GLI3;CYP2AA7;YY1B
protein-glutamic acid ligase activity	NEURL1B;ITCHA;MYLIPA;RAG1;SIAH2L;RNF187;MARCH5L;HECW2;RNF149
protein-glycine ligase activity	SHRPRBCK1R;MUL1A;MARCH5L;LTN1;RNF169;TRIM71;MARCH11;MGRN1A;SIAH2L
protein-glycine ligase activity, elongating	MARCH4;RNF180;TRIM71;RNF144AA;DTX1;MYLIPA;LTN1;ZNRF3;SIAH1A
protein-glycine ligase activity, initiating	TMEM129;TRIM50;HERC2;MARCH6;NEURL1B;NEURL3;G2E3;MGRN1A;MYLIPB
ribosomal S6-glutamic acid ligase activity	MYLIPA;DTX1;SIAH1A;UBR1;UBE2M;RNF149;NEURL1B;MGRN1A;RAG1
tubulin-glutamic acid ligase activity	NEURL3;RNF144AA;RNF149;TTLL1;MGRN1A;ZNRF3;RNF144AB;NEURL1B;MYLIPB
tubulin-glycine ligase activity	NEURL3;FLR;MARCH6;MYLIPB;RNF149;RNF144AB;TRIM71;ZNRF3;MGRN1A
ubiquitin-protein transferase activity	FBXO2;MIB2;TRIM9;RNF144B;SIAH2L;RBCK1;UBE2O;PARK2;UBE2D3
zinc ion binding	TRAF4;CPA3;RFFL;ZNF2;AQPEP;ALPI;ADAMTS15A;MPI;LMCD1

ZNRF3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ZNRF3 here. Most of them are supplied by our site. Hope this information will be useful for your research of ZNRF3.

Stinton, LM; Myers, RP; et al. Clinical associations and potential novel antigenic targets of autoantibodies directed against rods and rings in chronic hepatitis C infection. BMC GASTROENTEROLOGY 13:-(2013).

Xu, ZY; Nie, P; et al. Molecular identification and expression analysis of tumor necrosis factor receptor-associated factor 2 in grass carp Ctenopharyngodon idella. ACTA BIOCHIMICA ET BIOPHYSICA SINICA 39:857-868(2007).

E3 Ubiquitin Ligases