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ZW10

  • Official Full Name

    ZW10, kinetochore associated, homolog (Drosophila)

  • Overview

    This gene encodes a protein that is one of many involved in mechanisms to ensure proper chromosome segregation during cell division. This protein is an essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis.
  • Synonyms

    ZW10; ZW10, kinetochore associated, homolog (Drosophila); ZW10 (Drosophila) homolog, centromere/kinetochore protein; centromere/kinetochore protein zw10 homolog; KNTC1AP; Centromere/kinetochore protein zw10; HZW 10; HZW10; Kinetochore associated homolog; MGC149821; Zeste white 10; Zeste white 10 homolog; ZW 10; ZW 10 homolog centromere/kinetochore protein; ZW 10 kinetochore associated homolog; ZW10 (Drosophila) homolog centromere/kinetochore protein; ZW10 homolog centromere/kinetochore protein (Drosophila); ZW10 homolog centromere/kinetochore protein; ZW10 kinetochore associated homolog; ZW10_HUMAN; OTTHUMP00000238248; OTTHUMP00000238249; ZW10 homolog, centromere/kinetochore protein;

  • Cell & Tissue Lysates
  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • HEK293
  • HEK293T
  • Mammalian Cell
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • Myc|DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human ZW10-2102HCL Recombinant Human ZW10 cell lysate N/A
Human ZW10-762H Recombinant Human ZW10 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human ZW10-1065H Recombinant Human ZW10 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Mouse ZW10-19256M Recombinant Mouse ZW10 Protein Mammalian Cell His
Mouse ZW10-10510M-B Recombinant Mouse ZW10 Protein Pre-coupled Magnetic Beads HEK293
Mouse Zw10-7132M Recombinant Mouse Zw10 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse ZW10-10510M Recombinant Mouse ZW10 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat ZW10-6720R Recombinant Rat ZW10 Protein Mammalian Cell His
Rat ZW10-6376R Recombinant Rat ZW10 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat ZW10-6376R-B Recombinant Rat ZW10 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish ZW10-10491Z Recombinant Zebrafish ZW10 Mammalian Cell His
Chicken ZW10-6152C Recombinant Chicken ZW10 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • ZW10 Related Articles

ZW10 involved in several pathways and played different roles in them. We selected most pathways ZW10 participated on our site, such as Cell Cycle, Mitotic, M Phase, Mitotic Anaphase, which may be useful for your reference. Also, other proteins which involved in the same pathway with ZW10 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Cell Cycle, MitoticMCM8;CDCA8;CDKN2D;PHF8;CENPA;TMPO;NDEL1B;CEP135;TOP2A
M PhaseGORASP2;NDEL1;ENSAA;ITGB3BP;ZW10;KNTC1;CTDNEP1B;TMPO;CENPL
Mitotic AnaphaseCENPC1;ANKLE2;CENPQ;RCC2;SKA2;DSN1;CCDC99;WAPAL;CENPK
Mitotic Metaphase and AnaphaseNSL1;NUDC;CENPO;NUF2;MIS12;CENPH;RANGAP1B;KNTC1;SGOL1
Mitotic PrometaphaseNSL1;SGOL1;CENPI;NDEL1B;PMF1;SKA1;SPDL1;SMC4;SPC25
RHO GTPase EffectorsFMNL1;MIS12;CLIP1;RCC2;NCKAP1;NOXO1;RHOC;ZW10;RHPN2
RHO GTPases Activate ForminsNSL1;NUF2;SPC25;DIAPH1;RCC2;ZWINT;SPDL1;MIS12;SGOL2

ZW10 has several biochemical functions, for example, centromeric DNA binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ZW10 itself. We selected most functions ZW10 had, and list some proteins which have the same functions with ZW10. You can find most of the proteins on our site.

Function Related Protein
centromeric DNA bindingCENPC1;MSH3;KIF2C;MLH3;MSH2;CENPB;ZW10
protein bindingLRP12;SLC30A8;INADL;CLASP1;C18orf56;SOX14;APC2;NUFIP1;ARHGEF15

ZW10 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ZW10 here. Most of them are supplied by our site. Hope this information will be useful for your research of ZW10.

RINT1; ZWINT; NBAS

Bremner, KH; Scherer, J; et al. Adenovirus Transport via Direct Interaction of Cytoplasmic Dynein with the Viral Capsid Hexon Subunit. CELL HOST & MICROBE 6:523-535(2009).
Yee, JC; Gatti, MD; et al. Genomic and proteomic exploration of CHO and hybridoma cells under sodium butyrate treatment. BIOTECHNOLOGY AND BIOENGINEERING 99:1186-1204(2008).
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