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PAEP

  • Official Full Name

    progestagen-associated endometrial protein

  • Overview

    This gene is a member of the kernel lipocalin superfamily whose members share relatively low sequence similarity but have highly conserved exon/intron structure and three-dimensional protein folding. Most lipocalins are clustered on the long arm of chromosome 9. The encoded glycoprotein has been previously referred to as pregnancy-associated endometrial alpha-2-globulin, placental protein 14, and glycodelin, but has been officially named progestagen-associated endometrial protein. Three distinct forms, with identical protein backbones but different glycosylation profiles, are found in amniotic fluid, follicular fluid and seminal plasma of the reproductive system. These glycoproteins have distinct and essential roles in regulating a uterine environment suitable for pregnancy and in the timing and occurrence of the appropriate sequence of events in the fertilization process. A number of alternatively spliced transcript variants have been observed at this locus, but the full-length nature of only two, each encoding the same protein, has been determined.
  • Synonyms

    PAEP; progestagen-associated endometrial protein; glycodelin; alpha uterine protein; GD; GdA; GdF; GdS; glycodelin A; glycodelin F; glycodelin S; MGC138509; MGC142288; PAEG; PEP; PP14; PP14 protein (placental protein 14); pregnancy associated endometrial;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Native Proteins
  • Protein Pre-coupled Magnetic Beads
  • Bovine
  • Human
  • Pig
  • Rhesus Macaque
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Milk
  • Wheat Germ
  • His
  • His (Fc)
  • Avi
  • Myc
  • His|T7
  • DDK
  • N/A
  • N
  • GST
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human PAEP-31025TH Recombinant Human PAEP Wheat Germ N/A 180 amino acids
Human PAEP-7563H Recombinant Human PAEP, His-tagged E.coli His 19-180aa
Human PAEP-3470HCL Recombinant Human PAEP 293 Cell Lysate HEK293 N/A
Human PAEP-3469HCL Recombinant Human PAEP 293 Cell Lysate HEK293 N/A
Human PAEP-6549H Recombinant Human PAEP Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human PAEP-1893H Recombinant Human PAEP Protein, His&GST-tagged E.coli N-His&GST Met19-Phe158
Human PAEP-5048H Recombinant Human PAEP protein, His&Myc-tagged HEK293 His&Myc 19-180aa
Human PAEP-354HF Recombinant Full Length Human PAEP Protein In Vitro Cell Free System 180 amino acids
Human PAEP-4788H Recombinant Human PAEP Protein (Met19-Phe158), N-GST tagged E.coli N-GST Met19-Phe158
Bovine PAEP-04B Native Bovine PAEP Protein Milk
Bovine PAEP-0034B Recombinant Bovine PAEP Protein (Lys17-Ile178), N-His-tagged E.coli N-His Lys17-Ile178
Rhesus Macaque PAEP-3282R Recombinant Rhesus monkey PAEP Protein, His-tagged Mammalian Cell His
Rhesus Macaque PAEP-3100R-B Recombinant Rhesus Macaque PAEP Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque PAEP-3100R Recombinant Rhesus Macaque PAEP Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Pig PAEP-5750P Recombinant Pig PAEP protein, His & T7-tagged E.coli His/T7 Val19~Val178 (Accession # P04119)
  • Involved Pathway
  • Protein Function
  • Interacting Protein

PAEP involved in several pathways and played different roles in them. We selected most pathways PAEP participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with PAEP were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

PAEP has several biochemical functions, for example, protein binding, small molecule binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PAEP itself. We selected most functions PAEP had, and list some proteins which have the same functions with PAEP. You can find most of the proteins on our site.

Function Related Protein
protein bindingLPXN;GRAP2;CHMP1B;HSPB11;DOK6;CD59;ADAM1B;MBD4;CD28
small molecule bindingPTGDSB;MUP17;PTGDSA;APODA.2;MUP20;LCN2;AMBP;PAEP;LCN15

PAEP has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PAEP here. Most of them are supplied by our site. Hope this information will be useful for your research of PAEP.

GRAMD3; XRCC6; UBE2E1; EEF1A1; RIF1; COPS6; IGSF21; ESYT2; SLC25A12; DNAJB5; UBL4A; DDOST; SMAD3; GTF3C2; ZFP91

  • Q&As
  • Reviews

Q&As (5)

Ask a question
Are there any limitations or challenges associated with using PAEP protein in clinical settings? 12/21/2021

Challenges may include variations in individual PAEP levels and the need for standardized assays for accurate measurements.

Can PAEP protein be used as a marker for recurrent pregnancy loss? 05/31/2020

Some studies suggest a potential association between low PAEP levels and recurrent pregnancy loss, but more research is needed to establish a definitive link.

How does PAEP protein contribute to the understanding of endometrial function? 04/13/2019

PAEP's expression and regulation in the endometrium provide insights into the complex processes involved in implantation and endometrial function.

How is PAEP protein utilized in monitoring high-risk pregnancies? 01/10/2019

Elevated or reduced PAEP levels may indicate a risk of complications during pregnancy, such as preeclampsia, allowing for early intervention and management.

Can PAEP protein be a target for therapeutic interventions in reproductive medicine? 02/17/2016

Research suggests that manipulating PAEP levels may have therapeutic potential in addressing certain reproductive disorders, though further studies are needed.

Customer Reviews (3)

Write a review
Reviews
08/11/2020

    With the manufacturer's outstanding technical support, you can be assured that any challenges you encounter will be efficiently addressed.

    05/04/2020

      Its superior quality, combined with the manufacturer's exceptional technical support, provides researchers with the confidence they need to conduct successful experiments and obtain meaningful results.

      01/02/2019

        Researchers who have utilized the PAEP protein laud its reliability and effectiveness in their studies.

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