"Maurocalcine" Related Products

Synthetic Maurocalcine

Cat.No.: TOXPP-564S
Product Overview: This product is a potent agonist of ryanodine receptors with the formula of C156H260N56O46S6.
Description: Maurocalcine, a component of the venom of Scorpio maurus palmatus, was discovered by Michel De Waard. Maurocalcinefolds according to an inhibitor cysteine knot. Such asImperatoxin A, Maurocalcine acts as a high affinity agonist of thetype-1 ryanodine receptor expressed in skeletal muscles with an affinity in the 10 nM range. Maurocalcine induces an increase in channel opening probability accompanied by sudden transitions to long lasting subconductance states. Maurocalcine has also been characterized as a cell penetrating peptide and its pharmacological activity can be observed upon extracellular perfusion.
Source: Synthetic
Species: Synthetic
Form: White lyophilized solid
Molecular Mass: 3858.8 Da
Protein length: 33
AA Sequence: AA sequence: Gly-Asp-Cys3-Leu-Pro-His-Leu-Lys-Leu-Cys10-Lys-Glu-Asn-Lys-Asp-Cys16-Cys17-Ser-Lys-Lys-Cys21-Lys-Arg-Arg-Gly-Thr-Asn-Ile-Glu-Lys-Arg-Cys32-Arg-OH
Disulfide Bonds: Cys3-Cys17; Cys10-Cys21; Cys16-Cys32
Purity: > 98 %
Reconstitution: Water or saline buffer

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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