"&mu" Related Products

Synthetic μ-conotoxin-PIIIA

Cat.No.: TOXPP-514S
Product Overview: This product is a blocker of Nav1.4 channels with the formula of C103H165N40O28S6.
Description: μ-Conotoxin PIIIA(mu-conotoxin PIIIA) is aconotoxinthat has been isolated from the venom of the cone Conus purpurascens.μ-conotoxin PIIIAdemonstrates a higher affinity for the mammalian muscle sodium channel  Nav1.4  (IC50~ 44 nM) than for the CNS Nav1.2 subtype (IC50~ 640  nm). μ-Conotoxin PIIIAblocks  more  irreversibly amphibian  muscle  sodium  channels  than mammalian ones.
Source: Synthetic
Species: Synthetic
Form: White lyophilized solid
Molecular Mass: 2604.10 Da
Protein length: 22
AA Sequence: AA sequence: H-pGlu-Arg-Leu-Cys4-Cys5-Gly-Phe-Hyp-Lys-Ser-Cys11-Arg-Ser-Arg-Gln-Cys16-Lys-Hyp-His-Arg-Cys21-Cys22-NH2
Disulfide Bonds: Cys4-Cys16; Cys5-Cys21; Cys11-Cys22
Purity: > 97 %
Reconstitution: Water or saline buffer

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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