"NMB-1" Related Products

Synthetic NMB-1

Cat.No.: TOXPP-582S
Product Overview: This Synthetic NMB-1 has the formula of C111H164N36O21S4.
Description: NMB-1 (Noxious mechanosensation blocker 1) is an analogue of a peptide isolated from a marine conesnail. This 19 amino acid peptide has shown a 30 fold selectivity in inhibiting slowly adapting mechanically activated currents over rapidly adapting ones. It is an interesting tool to distinguish between RA and SA currents. NMB-1 significantly blocks SA currents at 1 µM in sensory neurons contrary to GsMTx4. Some results suggest that NMB-1 could also block mechanosensitive ion channels in cochlear hair cells at 5 µM. Creative BioMart is pleased to be the first company offering this research tool.
Source: Synthetic
Species: Synthetic
Form: White lyophilized solid
Molecular Mass: 2467.03 Da
Protein length: 19
AA Sequence: AA sequence: Phe-Asn-Trp-Arg-Cys-Cys-Leu-Ile-Pro-Cys-Arg-Arg-Asn-His-Lys-Lys-Phe-Phe-Cys-NH2
Disulfide Bonds: Cys5-Cys19; Cys6-Cys10
Purity: > 95 %
Reconstitution: Aqueous buffer

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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