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Interleukin-6 (IL-6)

Cat# : THP-0235

Product Datasheets COA :
Catalog# Product Name Availability Size Price Qty
THP-0235 Interleukin-6 (IL-6) March 29, 2024 1 vial $3,998.00
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Cat#:  THP-0235
Product Name:  Interleukin-6 (IL-6)
Description:  Recombinant Human IL-6 is a 20.9 kDa protein containing 184 amino acid residues.
Sequences:  PVPPGEDSKD VAAPHRQPLT SSERIDKQIR YILDGISALR KETCNKSNMC ESSKEALAEN NLNLPKMAEK DGCFQSGFNE ETCLVKIITG LLEFEVYLEY LQNRFESSEE QARAVQMSTK VLIQFLQKKA KNLDAITTPD PTTNASLLTK LQAQNQWLQD MTTHLILRSF KEFLQSSLRA LRQM
Species:  Human
Molecular Weight:  20.9 kDa
Source:  E. Coli
Introduction:  IL-6 is a pleiotropic cytokine that plays an important role in host defense by regulating immune and inflammatory responses. Produced by T cells, monocytes, fibroblasts, endothelial cells and keratinocytes, IL-6 has diverse biological functions. It stimulates B cell differentiation and antibody production, synergizes with IL-3 in megakaryocyte development and platelet production, induces expression of hepatic acute-phase proteins, and regulates bone metabolism. IL-6 signals through the IL-6 receptor system that consists of two chains, IL-6R α and gp130. Murine IL-6 is inactive on human cells, while both human and murine are equally active on murine cells.
Purity:  ≥ 98% by SDS-PAGE gel and HPLC analyses.
Biological Activity:  The ED50 as determined by the dose-dependent stimulation of the proliferation of IL-6 dependent murine 7TD1 cells is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 10^7units/mg.
For research use only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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  • Size: 100ug 500ug 1mg 5mg 10mg 100mg 500mg 1g
  • Conjugation: None R-PE APC Biotin FITC Alexa Flour Others
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