The Nobel Prize in Chemistry 2017 Awarded to Three Developers of Cryo-Electron Microscopy

nobelprize_2017_chem

The Nobel Prize in Chemistry 2017 was awarded to Jacques Dubochet, Joachim Frank, and Richard Henderson for their development of Cryo-Electron Microscopy (cryo-EM), which simplified and improved the imaging of biomolecules’ structure.   Did you notice, when you look at biochemical related news a certain period of time before, the pictures of the virus or other biomolecular structure just looked like the rough photos in old 3D horror games, or…

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The 2017 Nobel Prize in Physiology or Medicine Announced

NobelPrize

2017/10/02, the 2017 Nobel Prize in Physiology or Medicine jointly to Jeffrey C. Hall, Michael Rosbash and Michael W. Young for their discoveries of molecular mechanisms controlling the circadian rhythm. They will share 9 million Swedish kroner bonuses award. Jeffrey C. Hall, born in New York in 1945. 1971 received a Ph.D. from the University of Washington, 1971 to 1973 got post-doctoral position at the California Institute of Technology. In…

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Trispecific Antibodies Show Exceptional Potency Against Diverse HIV Viruses

HIV and antibody

According to the World Health Organization (WHO) statistics, in 2016, a total of about 36 million people suffering from human immunodeficiency disease in the world. Faced such a dilemma, in the efforts of scientists’ study, it seems have a breakthrough. A study on human immunodeficiency virus (HIV) antibody was published in the September 20, 2017 of the journal Science, which is an important milestone in HIV research. Researchers create am…

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Worldwide Mortality Rates: One in Five Deaths Linked to Poor Diet

Worldwide Mortality Rates

Recent study reveals: the number of deaths among children under five is decreasing. Though overall both men and women around the world are living longer, one in five deaths were linked to poor diet last year.   Life expectancy in 2016 worldwide was 75.3 years for women and 69.8 for men. Japan has the highest life expectancy at 84 years and the Central African Republic has the lowest at just…

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Cryo-EM Technique – Uncovered the Atomic Structure of a Key Alzheimer’s Protein for the First Time

alzehimer-2

Tau protein abnormal deposit is one of the most important characteristics for Alzheimer. Recently, a new finding published in Nature obtained high-resolution images of those protein deposit structures caused by Alzheimer and other neurodegenerative disease for the first time. These finding can help scientists understand how these protein harmful deposit process function at the molecular level, and help develop new treatments to prevent the formation of these proteins, and thus…

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Learn FDA’s Review of Bio-similar from ABP215

biosimilars

ABP215 is a biosimilar drug developed by Amgen and Allergan, using Avastin (bevacizumab) as a prototype drug. Amgen filed a drug application to the FDA in November 2016. The FDA Oncologic Drugs Advisory Committee (ODAC) met on July 13, 2017, and the members voted in favor of approving the ABP215 drug application. The ABP215 is expected to become America’s first Avastin bio-similar drug. Liu Shining, the research manager in TrendForce,…

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