Immune memory is a hallmark of the adaptive immune system in the body. Although natural killer cells (NK cells) are essential innate immune cells for the host’s immediate defense system, they can also differentiate into memory NK cells. Currently, researchers have not fully elucidated the molecular mechanisms behind controlling this differentiation process. Recently, a research report titled “Themis2 regulates natural killer cell memory function and formation” was published in the…
Month: December 2023
The Regulation of Cancer Stem Cells and Its Implications for Targeted Cancer Therapy
Tumor occurrence and progression are considered to be a complex progressive process involving multi-level reactions and accumulation of mutations. In the past few decades, there have been many studies on this topic in the field of oncology. These studies mainly focus on tumor cells, tumor microenvironment, tumor heterogeneity, etc., among which tumor heterogeneity is closely related to the occurrence and malignancy of tumors. Cancer stem cells (CSCs), as one of…
Molecular Mechanism behind MAF Protein Promoting Breast Cancer Metastasis
Breast cancer is the most common type of cancer among women. There are more than 2 million new cases of breast cancer every year. The survival rate of patients is very high, about 90%, when the tumor is still limited to breast tissue; however, when cancer cells spread beyond breast tissue and begin to form metastases in other organs, it significantly worsens the patient’s prognosis and poses great challenges to…
CDK4 Is Expected To Be Used In the Treatment of Type 2 Diabetes
Type 2 diabetes affects more than 500 million people worldwide. In a new study, researchers from Weill Cornell Medical College in the United States found a new pathway that stimulates insulin production in the preclinical diabetes model for healthy pancreas β cell growth. This discovery brings hope for future treatment, which will improve the life of patients with type 2 diabetes. The relevant research results have recently been published in…