To reveal the intricacies of how cells function, many assays work. However, nothing can compare to watching those process live in the cell. Then, numerous dyes and labels have been designed for live-cell imaging. But, even with this numerous choices, such studies are often complicated by toxic by toxic dyes, difficult labeling protocols, dye specificities and above all, phototoxicity following extended light exposure. In a recent study published in the…
Author: biomart
How Does Protein Accomplish “Dressing Up”?
It’s widely known that numerous of physiological and biochemical processes within cells are accomplished by protein. A tiny cell can contain millions of proteins which are translated and synthesized by ribosome. However, after synthesis, these protein molecules often have to undergo post-translational modification, which has important biological significance. Ubiquitinylation is one type of post-translational modification. In other words, after “dressing up” by some “junior partners”, proteins were sent for “mission”….
Nobel Prize to Women in Physiology or Medicine (Part Two)
In last post, we have give a brief introduction about the latest 5 woman Nobel laureates in Physiology or Medicine. This post is to cover the rest 7 excellent women. The 7th : Linda B. Buck Linda B. Buck (1947-), an American biologist best known for her work on the olfactory system. For their work on olfactory receptors, she along with Richard Axel, were awarded the 2004 Nobel Prize in…
Nobel Prize to Women in Physiology or Medicine (Part One)
October 5th, The Nobel prize in Physiology or Medicine was awarded one half jointly to William C. Campbell and Satoshi Ōmura for their discoveries concerning a novel therapy against infections caused by roundworm parasites and the other half to Youyou Tu for her discoveries relating to a novel therapy against Malaria. Since the invention of the Nobel Prize, only 11 women were awarded Nobel Prize in Physiology or Medicine….
What Makes Cancer So Fatal?
There exists, in some cancers, some abnormal cells similar to stem cells. These cells are as factories that are working overtime. They quickly produce a copy of their own and from time to time generate some variations. What’s worse, those cells can spread to other tissues of the body, and eventually leading to cancer metastasis. Researchers in Salk institution found that, Sox10 can determine whether cells will transform into…
Pesticides Linked to Increased Diabetes Risk
Previously, it has been revealed that the use of certain pesticides at home might increase the risk of childhood cancer. However, a recent study claimed that pesticides are also linked to increased risk of diabetes. The report said that long-term exposure to pesticides can significantly increase the risk of type 2 diabetes (60 percent). “Our study suggests that pesticides can significantly increase the risk of developing type 2 diabetes, even…
Month-end Check: Biotech study topics in Nature-September
Giant study poses DNA data-sharing dilemma A commonly discussed issue: should the information about disease risk, especially genetic data be shared with participants. Some say participants should at least have the right to know their personal data to investigate their own health, but some specialists say showing participants their data is irresponsible for the information can’t be interpreted by every person. The significance is always uncertain. People who get know…
Cytokine and Receptor Analysis in Creative BioMart
Cytokine receptors are receptors that bind cytokines. In recent years, cytokine receptors have caught much more attentions than cytokines themselves. Maybe this is because of their remarkable characteristics or because a deficiency of cytokine receptors has now been directly linked to certain debilitating immunodeficiency states. Creative BioMart, a world leading biotech company dedicated to providing quality custom analytical and translational services, has a revolutionary new platform designed for enrichment and highly…
On the Three Revolutions of Cancer Research
So far, cancer drug development has gone through three huge revolutions; they are: cytotoxic chemotherapy drugs, “targeted therapy” and immunotherapy. Immunotherapy has not only revolutionized the effectiveness of cancer treatment and will revolutionize the concept of cancer treating. Relatively speaking, immunotherapy is the real anti-cancer revolution and the most reasonable means to solve cancer. Chemotherapy- the first revolution of anti-cancer drugs Starting from 1940, the most used anti-cancer chemotherapy…
Pesticides May Increase Children’s Cancer Risk
According to a recent study published in Pediatrics, the use of certain pesticides at home might increase the risk of childhood cancer. In this analysis, scientists studied the potential links between the exposure to household pesticides and . To their surprise, they found that children exposed to indoor pesticides has 47 larger percentage of suffering from leukemia in the juvenile than those who never touched pesticides. And the risk of…