JEM: Prevent Exhaustion in Immune Cells Boosts Immunotherapy

If you are an immune cell ready to fight cancer, you’d better eat some breakfast. Because the tumor microenvironment is a harsh place, and tumor cells are always ready to make you exhausted.   Improvement of highly specific immune fighter in vivo: The ability of T cells to attack tumors has achieved clinically significant advances in tumor immunotherapy. However, this method is only effective in 10-30% of patients. One reason…

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Nature Communication: Proteins that Make Difference between Cancerous and Healthy Cells Found

A recent study published in Nature Communication reveals how cancerous cells differ from healthy ones, which paves way for the development of novel strategies for the therapeutic intervention for difficult-to-treat cancers in the future.   An international research team discovered a “stop sign”- a mutated protein called PIP-stop, which is overused by tumor cells and can effectively prevent healthy cells from classifying in the way they are designed to.  …

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