PNAS: Obese Hormones Increase the Risk of Sepsis

Scientists from the Gulbenkian de Ciência Institute (IGC) led by Luís Moita have discovered that a hormone believed to treat obesity reduces the body’s resistance to bacterial infections and increases the risk of sepsis. The research results were recently published in PNAS.   Sepsis is a potentially fatal disease that stems from the dysregulation of the organism’s response to infection, leading to organ failure. A recent study published in the…

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Loss of Fat-regulated Genes Accelerates Metastatic Spread of Prostate Cancer

Researchers at the Department of Radiation Oncology and Molecular Radiology at the Kimmel Cancer Center at Johns Hopkins University have discovered a lipid-modulating protein that transfers a substance that researchers call “superpower” to prostate cancer cells, allowing them to spread malignantly.   In studies of human prostate cancer cells and stromal cell lines, when the lipid regulatory protein called CAVIN1 was removed from stromal cells (connective tissue cells in and…

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