In a research report entitled “Specific inhibition of the Survivin – CRM1 interaction by peptide modified molecular tweezers” published in the journal Nature Communications, scientists from Eisen University in Duisburg and other institutions revealed how to turn off the “survival protein” in cancer cells through research. Proteins can control almost all the key physiological processes in the body cells. If they do not function normally and become more or less,…

PD-1 inhibitors restore the activity of tumor-responsive CD8 + T cells by eliminating the inhibition induced by PD-1 and PD-L1 interaction. This therapy has brought great changes to cancer treatment, but only a few patients can benefit from this therapy. There is evidence that the lack of effective T cell activation may be one of the reasons.   In a study published in nature communications, researchers from the Institute of…