Recently, there are two articles which reported the study on CXCL12 and breast cancer. Let’s take a glance on these new results. Breast cancer (BC) remains the most frequent cancer and the major cause of cancer-associated death in women. Based on histopathological analysis commonly used in clinical practice, BC has been identified as a heterogeneous disease classified into three main subtypes: Luminal (Lum), HER2 and triple-negative (TN), which have been…
Cancer research
Akt Protein Suppressed by pVHL Protein through Proline-hydroxylation–dependent Manner
Jianping Guo et al. studied the relationship between VHL protein and Akt protein, and their published their research results on Science Magazine (Science 26 Aug 2016: Vol. 353, Issue 6302, pp. 929-932 DOI: 10.1126/science.aad5755). Here we share this wonderful article hoping to help your research applications. Don’t forget that Creative Biomart provides VHL protein and Akt protein related molecular tools for you as always. [table caption=”Related Products” width=”800″ colwidth=”80|280|180″ colalign=”left|left|center|center|center”] Cat….
Therapeutic Targets for Skin Cancer: MET Signaling and RAS Converge on EGFR
New findings from Science Signaling (21 Jun 2016: Vol. 9, Issue 433, pp. ra62 DOI: 10.1126/scisignal.aaf5106), this article indicates that EGFR pathway may offer potential therapeutic targets for patients. Here we provide part of this wonderful article. Read full details: http://stke.sciencemag.org/content/9/433/ra62. [table caption=”Related Products” width=”800″ colwidth=”100|250|180″ colalign=”left|center|center|center|center”] No.,Gene name,Product type,Product number 1,EGFR,Recombinant Protein,48 2,MET,Recombinant Protein,42 3,HGF,Recombinant Protein,30 4,HRAS,Recombinant Protein,19 [/table] Introduction Studies using the multistage induction of squamous cancers on…
A Collective Route to Metastasis: Seeding by Tumor Cell Clusters
Metastasis is the one of the biggest challenges in cancer therapy. Here we share part of a latest article which discusses the nature of the tumor cells that give rise to metastases by Kevin J. Cheung and Andrew J. Ewald. The origin of this article is Science 08 Apr 2016: Vol. 352, Issue 6282, pp. 167-169 (DOI: 10.1126/science.aaf6546) where you can get the full article. Also Creative Biomart provides molecular tools…
Pigeons that Can Distinguish Cancer Image
In nature, numerous animals share characteristics with humans, such as pigeons, its ability to find ways still remains for human use. However, a recent study makes people aware it’s more than that. Richard Levenson, pathologists from the United States together with Edward Wasserman, psychologist from Edward Wasserman, trained pigeons to identify cancer. During training, the researchers first demonstrated the microscope image of breast tissue to pigeon. Then, the…
New mechanism of pRb Found
A recent study has found new mechanism of pRb-a well know tumor suppressor. The research completed by scientists at University of Illinois in the United States and Spain Pompeu Fabra University, was published in International academic journals Gene & Development. Tumor suppressor is a kind of protein that acts as natural “brake” for cellular proliferation, having the ability to prevent the formation of malignant tumors. Depth understanding of how these…
What Makes Cancer So Fatal?
There exists, in some cancers, some abnormal cells similar to stem cells. These cells are as factories that are working overtime. They quickly produce a copy of their own and from time to time generate some variations. What’s worse, those cells can spread to other tissues of the body, and eventually leading to cancer metastasis. Researchers in Salk institution found that, Sox10 can determine whether cells will transform into…
On the Three Revolutions of Cancer Research
So far, cancer drug development has gone through three huge revolutions; they are: cytotoxic chemotherapy drugs, “targeted therapy” and immunotherapy. Immunotherapy has not only revolutionized the effectiveness of cancer treatment and will revolutionize the concept of cancer treating. Relatively speaking, immunotherapy is the real anti-cancer revolution and the most reasonable means to solve cancer. Chemotherapy- the first revolution of anti-cancer drugs Starting from 1940, the most used anti-cancer chemotherapy…
Pesticides May Increase Children’s Cancer Risk
According to a recent study published in Pediatrics, the use of certain pesticides at home might increase the risk of childhood cancer. In this analysis, scientists studied the potential links between the exposure to household pesticides and . To their surprise, they found that children exposed to indoor pesticides has 47 larger percentage of suffering from leukemia in the juvenile than those who never touched pesticides. And the risk of…
Cell launched Four Featured Cancer Immunotherapy Reviews
Although it has been years since the idea of using immune system to fight against cancer come into being, only until recent years do scientists find some successful treatment strategies. By manipulating the immune checkpoints and T cell activation to exert anti-tumor activity, immunotherapy has been applied to a wider range of malignancies now, while it only showed therapeutic potential in several types of cancers in the very beginning. Recently…