According to the World Health Organization (WHO) statistics, in 2016, a total of about 36 million people suffering from human immunodeficiency disease in the world. Faced such a dilemma, in the efforts of scientists’ study, it seems have a breakthrough. A study on human immunodeficiency virus (HIV) antibody was published in the September 20, 2017 of the journal Science, which is an important milestone in HIV research. Researchers create am…
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Worldwide Mortality Rates: One in Five Deaths Linked to Poor Diet
Recent study reveals: the number of deaths among children under five is decreasing. Though overall both men and women around the world are living longer, one in five deaths were linked to poor diet last year. Life expectancy in 2016 worldwide was 75.3 years for women and 69.8 for men. Japan has the highest life expectancy at 84 years and the Central African Republic has the lowest at just…
Cryo-EM Technique – Uncovered the Atomic Structure of a Key Alzheimer’s Protein for the First Time
Tau protein abnormal deposit is one of the most important characteristics for Alzheimer. Recently, a new finding published in Nature obtained high-resolution images of those protein deposit structures caused by Alzheimer and other neurodegenerative disease for the first time. These finding can help scientists understand how these protein harmful deposit process function at the molecular level, and help develop new treatments to prevent the formation of these proteins, and thus…
Learn FDA’s Review of Bio-similar from ABP215
ABP215 is a biosimilar drug developed by Amgen and Allergan, using Avastin (bevacizumab) as a prototype drug. Amgen filed a drug application to the FDA in November 2016. The FDA Oncologic Drugs Advisory Committee (ODAC) met on July 13, 2017, and the members voted in favor of approving the ABP215 drug application. The ABP215 is expected to become America’s first Avastin bio-similar drug. Liu Shining, the research manager in TrendForce,…
Antiviral Proteins Designed by Computer May Help Halt Pandemic
Bill Gates said in a speech at the Munich Security Conference that three threats are closely related to the fate of our human species: nuclear warfare, climate change and the next global pandemic. “If we are going to prepare for the worst, we should build an arsenal.” The factory he mentioned is not referring to any guns or ammunition, but the vaccine, drugs and diagnostics. At present, what troubles us…
Tea and Coffee Consumption in Relation to DNA Methylation
In a recent study published in Human Molecular Genetics, researchers from the University of Uppsala, found that tea consumption may lead to DNA methylation changes of some special genes in women bodies, while those genes are thought to have interactions between cancers and estrogen metabolism. As we all know, lifestyle factors, like food choices, smoking and exposure to chemicals, can alter DNA methylation and lead to changes in gene…
Would You Accept a Pig’s Heart One Day?
Imagine: your heart is failing to work, and a replacement is deadly in need. Consistently, your family waits anxiously for a call from the hospital for the found of donor. At that point, one day, the call comes. In your fervor you scarcely hear what the doctor on the flip side of the line is letting you know. There’s something you ought to know, she says. The contributor is not…
Body Weight, Appetite and Lipocalin
Body weight is determined by energy balance. When the energy intake equals energy expenditure, the body weight remains unchanged. On the other hand, the body weight grow when the energy surplus. Energy balance is critical for survival and health, and control of food intake is an integral part of this process. Excess energy intake has become a scapegoat for the obesity epidemic in developed countries. While it is responsible in…
XRCC1 Mutation Is Associated With Cerebellar Ataxia
Cerebellar ataxia can occur as a result of many diseases and presents with symptoms of an inability to coordinate balance, gait, extremity and eye movements. There are many causes of cerebellar ataxia including, among others, autoimmunity to Purkinje cells or other neural cells in the cerebellum, CNS vacuities, multiple sclerosis, infection, bleeding, infarction, tumors, direct injury, toxins, genetic disorders, and an association with statin use. Inherited (genetic) forms of ataxia…
How About The Biological Science Funding Going Under Trump?
After the long campaign for the White House, Donald Trump became the new president of US. With just two months before his inauguration on 20 January, he and his staff are busy vetting candidates for top government jobs and clarifying the agenda for his first few months in office. We are waiting to see how Trump realizes his statements during the campaign. The most concerning thing for us is the…