TRPC can significantly regulate the pathogenesis of endotoxemia

Recently, Professor Cao Wei’s team from the School of Chemistry and Pharmacy of Northwest Agriculture and Forestry University published a paper entitled “TRPC channels blockade organisms endotoxic cardiac dysfunction by hamming intelligent inflammation and Ca2+ leakage” in Nature Communications.   This study revealed that the classical transient receptor potential channel (TRPC) subtypes 1 and 6 can significantly regulate the cardiac inflammatory cascade reaction induced by endotoxin, thus playing a key…

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